{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:13:22Z","timestamp":1790630002328,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T00:00:00Z","timestamp":1698192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The benefits of lymph node (LN) dissection at each station have not previously been fully investigated in perihilar cholangiocarcinoma (PHCC) and distal cholangiocarcinoma (DCC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The efficacy index (EI) was calculated in patients who underwent surgery for PHCC (<jats:italic>n<\/jats:italic>\u2009=\u2009134) and DCC (<jats:italic>n<\/jats:italic>\u2009=\u2009135) by multiplying the frequency of metastasis to the LN station and the 5\u2010year overall survival (OS) rate of patients with metastasis to that station.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In PHCC, the frequency of metastasis, 5\u2010year OS rates, and the EI in para\u2010aortic LNs (4.7%, 0%, and 0, respectively) and posterior pancreaticoduodenal LNs (8.1%, 0%, and 0, respectively) were lower than those in hepatoduodenal ligament LNs (30.1%, 24.1%, and 7.25, respectively) and LNs along the common hepatic artery (CHA) (16.2%, 15.0%, and 2.43, respectively). In DCC, these values were lower in LNs along the CHA (6.4%, 0%, and 0, respectively) than in the posterior pancreaticoduodenal LNs (31.2%, 34.5%, and 10.8, respectively), the hepatoduodenal ligament LNs (14.8%, 15.2%, and 2.25, respectively), and para\u2010aortic (4.0%, 25.0%, and 0.99, respectively) LNs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>According to the EI, this study raises concerns about the effectiveness of dissection in the posterior pancreaticoduodenal LNs in PHCC and LNs along the CHA in DCC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.1387","type":"journal-article","created":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T08:19:46Z","timestamp":1698221986000},"page":"251-261","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Benefit of lymph node dissection for perihilar and distal cholangiocarcinoma according to lymph node stations"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1562-3265","authenticated-orcid":false,"given":"Fumihiro","family":"Terasaki","sequence":"first","affiliation":[{"name":"Division of Hepato\u2013Biliary\u2013Pancreatic Surgery Shizuoka Cancer Center  Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7163-4084","authenticated-orcid":false,"given":"Teiichi","family":"Sugiura","sequence":"additional","affiliation":[{"name":"Division of Hepato\u2013Biliary\u2013Pancreatic Surgery Shizuoka Cancer Center  Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3384-2709","authenticated-orcid":false,"given":"Yukiyasu","family":"Okamura","sequence":"additional","affiliation":[{"name":"Division of Hepato\u2013Biliary\u2013Pancreatic Surgery Shizuoka Cancer Center  Shizuoka 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