{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T12:04:59Z","timestamp":1765713899071},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,11,30]],"date-time":"2014-11-30T00:00:00Z","timestamp":1417305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Healthcare cost modeling have favored early (<jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content>) over interval laparoscopic cholecystectomy (<jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content>) for acute cholecystitis (<jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>). However, actual costs of treatment have never been studied. The aim of the present study was to compare actual hospital costs involved in <jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content> in patients with <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study of patients who underwent laparoscopic cholecystectomy for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> was conducted. Demographic, clinical, operative data and costs were extracted and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between 2011 and 2013, 201 had laparoscopic surgery for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> at <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>an <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ock <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eng <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ingapore. One hundred and thirty\u2010four (67%) patients underwent <jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content> (\u22647 days of presentation, within index admission). Median total length of stay (<jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content>) was 4.6 and 6.8 days for <jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content> groups, respectively (<jats:italic>P<\/jats:italic> = 0.006). Patients who had <jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content> also had significantly lesser total number of admissions (<jats:italic>P<\/jats:italic> &lt; 0.001). The median (<jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>) total inpatient costs were \u20ac4.4 \u00d7 10<jats:sup>3<\/jats:sup> (3.6\u20135.6) and \u20ac5.5 \u00d7 10<jats:sup>3<\/jats:sup> (4.0\u20137.5) for <jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content> patients, respectively (<jats:italic>P<\/jats:italic> &lt; 0.007). Costs associated with investigations were significantly higher in the <jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content> group (<jats:italic>P<\/jats:italic> = 0.039), of which serological costs made most difference (<jats:italic>P<\/jats:italic> &lt; 0.005). The ward costs were also significantly higher in the <jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content> group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The cost differences reflect the significantly increased total <jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content>, and repeat presentations associated with <jats:styled-content style=\"fixed-case\">ILC<\/jats:styled-content>. Therefore, <jats:styled-content style=\"fixed-case\">ELC<\/jats:styled-content> should be the preferred management strategy for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.196","type":"journal-article","created":{"date-parts":[[2014,11,30]],"date-time":"2014-11-30T23:54:39Z","timestamp":1417391679000},"page":"237-243","source":"Crossref","is-referenced-by-count":11,"title":["Analysis of actual healthcare costs of early versus interval cholecystectomy in acute cholecystitis"],"prefix":"10.1002","volume":"22","author":[{"given":"Cheryl H. M.","family":"Tan","sequence":"first","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Annex 1, 11 Jalan Tan Tock Seng Singapore 308433"},{"name":"School of Medicine University of Aberdeen  Aberdeen Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony C. Y.","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Annex 1, 11 Jalan Tan Tock Seng Singapore 308433"},{"name":"Discipline of Surgery Sydney Medical School The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winston W. L.","family":"Woon","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Annex 1, 11 Jalan Tan Tock Seng Singapore 308433"},{"name":"School of Medicine National University of Singapore  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee Keem","family":"Low","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Annex 1, 11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer P.","family":"Junnarkar","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Annex 1, 11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6870"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.143.6.533"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005440.pub2"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-005-0100-2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-255X(03)00065-9"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-003-9230-6"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00708.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199804000-00001"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-012-0567-x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4831"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(02)00789-4"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1996.01430170086016"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900008"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90674-E"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2004.06.013"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02826.x"},{"key":"e_1_2_8_18_1","first-page":"20","article-title":"Consequences of prolonged wait before gallbladder surgery","volume":"84","author":"Cheruvu CV","year":"2002","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2430-1"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6872"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6685"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-006-1159-4"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b13ca2"},{"key":"e_1_2_8_24_1","first-page":"10","article-title":"The true cost of gallstone disease","volume":"81","author":"Jones C","year":"2012","journal-title":"Ulster Med J"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900360"}],"container-title":["Journal of Hepato-Biliary-Pancreatic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjhbp.196","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jhbp.196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T05:02:14Z","timestamp":1696482134000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jhbp.196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,30]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1002\/jhbp.196"],"URL":"https:\/\/doi.org\/10.1002\/jhbp.196","archive":["Portico"],"relation":{},"ISSN":["1868-6974","1868-6982"],"issn-type":[{"value":"1868-6974","type":"print"},{"value":"1868-6982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,30]]}}}