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We compared the JPN 2015 with the other two guidelines, International Association of Pancreatology (IAP)\/American Pancreas Association (APA) 2013 and American College of Gastroenterology (ACG) 2013, in order to clarify the distinct points.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The meta\u2010analysis team conducted a new meta\u2010analysis of four subjects that have been associated with conflicting results. It is apparent that the revised guidelines have been created more systematically and more objectively. As of antibiotics prophylaxis, its use in early phase (within 72\u2009h of onset) for severe acute pancreatitis is recommended in JPN 2015 according to the results of original meta\u2010analysis, whereas the other two guidelines do not recommend its routine use. An approach and management of local complications in necrotizing pancreatitis including infected necrosis are almost similar in the three guidelines. JPN 2015 alone emphasizes the implementation of the pancreatitis bundles that specify the management and treatment within the first 48\u2009h after the onset of severe acute pancreatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The JPN Guidelines 2015 prove to be the highest quality in terms of systematic literature review conducting original analyses by the meta\u2010analysis team, determining the grading of recommendations and providing pancreatitis bundles.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.260","type":"journal-article","created":{"date-parts":[[2015,4,22]],"date-time":"2015-04-22T05:07:21Z","timestamp":1429679241000},"page":"433-445","source":"Crossref","is-referenced-by-count":53,"title":["Revised Japanese guidelines for the management of acute pancreatitis 2015: revised concepts and updated points"],"prefix":"10.1002","volume":"22","author":[{"given":"Shuji","family":"Isaji","sequence":"first","affiliation":[{"name":"Hepatobiliary Pancreatic &amp; Transplant Surgery Mie University Graduate School of Medicine  2\u2010174 Edobashi Tsu Mie 514\u20108507 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadahiro","family":"Takada","sequence":"additional","affiliation":[{"name":"Department of Surgery Teikyo University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Mayumi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine University of Occupational and Environmental Health  Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Hemodialysis and Surgery, Chemotherapy Research Institute International University of Health and Welfare  Ichikawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Wada","sequence":"additional","affiliation":[{"name":"Department of Surgery Teikyo University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Yokoe","sequence":"additional","affiliation":[{"name":"General Internal Medicine Japanese Red Cross Nagoya Daini Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Itoi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshifumi","family":"Gabata","sequence":"additional","affiliation":[{"name":"Department of Radiology, School of Medical Science Kanazawa University  Kanazawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpa.0000236733.31617.52"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-005-1047-3"},{"key":"e_1_2_8_4_1","unstructured":"ShimosegawaT.Summary of reports from 2011 to 2013 by The Intractable Pancreatic Disease Investigation and Research Group of the Japanese Ministry of Health Labour and Welfare 2014. p. 61\u201373. 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