{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:22:25Z","timestamp":1791638545621,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T00:00:00Z","timestamp":1495497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Japanese Society of Hepato-Biliary-Pancreatic Surgery"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The collaborative multicenter retrospective study of acute cholecystitis (<jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>) was performed in Japan and Taiwan. The aim for this study was evaluation of the clinical value of <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>13 severity grading for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The study was designed as an international multicenter retrospective study of <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> from 2011 to 2013. Based on the data, we investigated the <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>13 severity grading by analyzing the correlations between grade and prognosis, surgical procedures, histopathology, and organ dysfunction and prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>An investigation revealed that 30\u2010day overall mortality rate was 1.1% for Grade I, 0.8% for Grade <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>, 5.4% for Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>. The mortality rate for Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> was significantly higher than lower grades (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). The greater the number of organ dysfunction, the higher the mortality rate (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). However, the mortality rate varied depending on the number of organ dysfunction (3.1\u201325%). With respect to the surgical procedures, laparoscopic cholecystectomy was performed for Grade I patients (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), and the higher the grade, the more likely open surgery would be selected (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>13 severity grading criteria for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> are providing great benefits in actual clinical settings. From this study, the position of each severity grade was obviously confirmed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.457","type":"journal-article","created":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T07:42:44Z","timestamp":1492414964000},"page":"338-345","source":"Crossref","is-referenced-by-count":47,"title":["Validation of <scp>TG<\/scp>13 severity grading in acute cholecystitis: Japan\u2010Taiwan collaborative study for acute cholecystitis"],"prefix":"10.1002","volume":"24","author":[{"given":"Masamichi","family":"Yokoe","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine Japanese Red Cross Nagoya Daini Hospital Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadahiro","family":"Takada","sequence":"additional","affiliation":[{"name":"Department of Surgery Teikyo University School of Medicine Tokyo 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Mayumi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine School of Medicine University of Occupational and Environmental Health Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rintaro","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Health Policy National Center for Child Health and Development Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miin\u2010Fu","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of General Surgery Lin\u2010Kou Chang Gung Memorial Hospital Tauyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Yin","family":"Jan","sequence":"additional","affiliation":[{"name":"Division of General Surgery Lin\u2010Kou Chang Gung Memorial Hospital Tauyuan 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