{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:00:43Z","timestamp":1787223643454,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:00:00Z","timestamp":1542758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of the present study was to investigate the characteristics, management, and outcomes of congenital biliary dilatation (<jats:styled-content style=\"fixed-case\">CBD<\/jats:styled-content>) in neonates and infants (&lt;1 year old) in a single institution over the past 20 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From 1997 to 2016, 21 patients &lt;1 year old underwent definitive surgery for <jats:styled-content style=\"fixed-case\">CBD<\/jats:styled-content>. Open surgery (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>) was performed between 1997 and 2008, and laparoscopic surgery (<jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>) has been performed since 2009.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The bile duct showed cystic dilatation in all patients. Sixteen (76.2%) of the 21 patients were diagnosed prenatally, and the incidence increased with time (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> 63.6%, <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> 90%). Fourteen patients (66.7%) were symptomatic before surgery, with jaundice in 11 (52.4%), acholic stool in seven (33.3%), and vomiting in three (14.3%). There were no significant differences in operation time and blood loss, but the postoperative fasting period and hospital stay were significantly shorter in the <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> group (<jats:italic>P<\/jats:italic> &lt; 0.05). There were no intraoperative complications, but there was one postoperative early complication in one <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> group patient, who had bile leakage and was treated with redo hepaticojejunostomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidences of prenatally diagnosed and asymptomatic patients increased with time. Although longer follow\u2010up is needed, <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">CBD<\/jats:styled-content> could be safely performed even in neonates and early infants.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.590","type":"journal-article","created":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T04:23:37Z","timestamp":1539750217000},"page":"544-549","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Characteristics, management, and outcomes of congenital biliary dilatation in neonates and early infants: a 20\u2010year, single\u2010institution study"],"prefix":"10.1002","volume":"25","author":[{"given":"Naoto","family":"Urushihara","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Shizuoka Children's Hospital 860 Urushiyama, Aoi\u2010ku Shizuoka 420\u20108660 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