{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T01:48:29Z","timestamp":1766627309756},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although there are many studies on technical outcomes of endoscopic nasobiliary drainage (ENBD), no authors reported on preoperative course of patients undergoing ENBD. The aim of this study was to investigate the course of patients with ENBD during the waiting period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent resection of perihilar cholangiocarcinoma (PHCC) between January 2013 and September 2017 were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 191 consecutive patients underwent surgical resection of PHCC after ENBD. Of the study patients, 154 (80.6%) patients were discharged, returned to their home, then re\u2010admitted for surgery. The remaining 37 patients were continuously hospitalized. The number of cholangitis events during the waiting period was 0 in 120 patients, 1 in 59 patients, 2\u00a0\u2264\u00a0in 12 patients. Endoscopic re\u2010intervention was needed in 52 patients. The median length between the first admission and surgery was 37\u00a0days (range 12\u2013197\u00a0days) in the entire cohort; it was longer in patients with portal vein embolization than in those without (43 vs. 27\u00a0days, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients undergoing resection of PHCC, ENBD is widely tolerable with relatively low incidence of cholangitis and thus recommended for preoperative biliary drainage.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.640","type":"journal-article","created":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T03:33:04Z","timestamp":1559532784000},"page":"341-347","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Preoperative course of patients undergoing endoscopic nasobiliary drainage during the management of resectable perihilar cholangiocarcinoma"],"prefix":"10.1002","volume":"26","author":[{"given":"Takashi","family":"Maeda","sequence":"first","affiliation":[{"name":"Division of Surgical Oncology Department of Surgery Nagoya University Graduate School of Medicine 65 Tsurumai-cho, Showa-ku Nagoya Aichi 466-8550 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Ebata","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Department of Surgery Nagoya University Graduate School of Medicine 65 Tsurumai-cho, Showa-ku Nagoya Aichi 466-8550 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Department of Surgery Nagoya University Graduate School of Medicine 65 Tsurumai-cho, Showa-ku Nagoya Aichi 466-8550 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