{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:01:03Z","timestamp":1784887263041,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Laparoscopic common bile duct exploration (LCBDE) treats choledocholithiasis whilst avoiding morbidity associated with endoscopic retrograde cholangiopancreatography (ERCP). This study compared outcomes of LCBDE in patients aged &lt;\u200970\u2009years and \u2265\u200970\u2009years at a high\u2010volume specialist center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective analysis of a prospectively maintained database was performed for patients undergoing LCBDE between January 2011 and September 2024. Patients were stratified by age (&lt;\u200970 vs. \u2265\u200970\u2009years). Primary outcome was complete bile duct clearance. Secondary outcomes included operative time, length of stay (LOS), 30\u2010day morbidity (Clavien\u2013Dindo), conversion to open surgery, readmission, and retained stones. Statistical analyses used Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      and\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      or Fisher's exact tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Four hundred and ninety\u2010four patients underwent LCBDE (375\u2009&lt;\u200970\u2009years; 119\u2009\u2265\u200970\u2009years). Elderly patients had higher ASA grades and Charlson Comorbidity Index scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Complete ductal clearance was achieved in 99.5% of younger and 100% of elderly patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.20). Conversion to open surgery occurred in six patients. No perioperative mortality was observed. Median LOS was longer in elderly patients (3 vs. 2\u2009days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Thirty\u2010day morbidity did not differ significantly between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LCBDE is a safe and effective treatment for choledocholithiasis in selected elderly patients when performed in specialist centers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhbp.70112","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T06:44:15Z","timestamp":1775717055000},"page":"548-556","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Safety and Outcomes of Laparoscopic Common Bile Duct Exploration in Elderly Patients: A Retrospective Comparative Cohort Study From a High\u2010Volume Specialist Centre"],"prefix":"10.1002","volume":"33","author":[{"given":"Matthew","family":"Brazkiewicz","sequence":"first","affiliation":[{"name":"Department of Pancreaticobiliary and Robotic Surgery University Hospitals of Derby &amp; Burton  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8993-6547","authenticated-orcid":false,"given":"Javed","family":"Latif","sequence":"additional","affiliation":[{"name":"Department of Pancreaticobiliary and Robotic Surgery University Hospitals of Derby &amp; Burton  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Pancreaticobiliary and Robotic Surgery University Hospitals of Derby &amp; Burton  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imran","family":"Bhatti","sequence":"additional","affiliation":[{"name":"Department of Pancreaticobiliary and Robotic Surgery University Hospitals of Derby &amp; Burton  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9644-1967","authenticated-orcid":false,"given":"Altaf","family":"Awan","sequence":"additional","affiliation":[{"name":"Department of Pancreaticobiliary and Robotic Surgery University Hospitals of Derby &amp; Burton  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-312317"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2020.12.048"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70025-4"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-023-04149-w"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-5257-3"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-06914-8"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2021.0355"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(91)70740-2"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2001.117550"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2002.02291.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01279.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966723"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2018.09.004"},{"issue":"10","key":"e_1_2_10_15_1","first-page":"4656","article-title":"Comparison of Laparoscopic Common Bile Duct Exploration and Endoscopic Retrograde Cholangiopancreatography Combined With Laparoscopic Cholecystectomy for Patients With Gallbladder and Common Bile Duct Stones a Meta\u2010Analysis of Randomized Controlled Trials","volume":"27","author":"Lan W. 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