{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T19:26:50Z","timestamp":1787081210844,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["HI22C1880"],"award-info":[{"award-number":["HI22C1880"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to evaluate the association between perioperative blood transfusion and postoperative mortality in patients undergoing pancreatic surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study used the Korean National Health Insurance Service database to identify patients who underwent pancreatic surgery (2012\u20132020). Transfusion was defined as the administration of \u2265\u20091 pack of whole blood or red blood cells within 7\u2009days before to 30\u2009days after surgery. Baseline characteristics were balanced using propensity score matching, and mortality risk was assessed using Cox proportional hazards models. Subgroup analyses were performed by surgical type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 26 175 patients were included, and 36.1% received transfusion. After matching, mortality remained higher in the transfusion group (63.3% vs. 52.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). Adjusted hazard ratios (aHRs) remained elevated across follow\u2010ups: 45\u2009days, 9.9 (95% CI, 1.0\u201396.1); 6\u2009months, 3.0 (1.9\u20134.8); and 5\u2009years, 1.4 (1.3\u20131.6). Subgroup analyses showed increased short\u2010 and long\u2010term mortality risk in pancreaticoduodenectomy, with an overall aHR of 1.4 (1.2\u20131.6). In contrast, no long\u2010term mortality risk was observed in distal pancreatectomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Perioperative transfusion was associated with increased mortality after pancreatic surgery. These findings indicate the need for prudent transfusion practices and patient blood management strategies tailored to the surgical type to minimize transfusion\u2010related risks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhbp.70116","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T01:45:08Z","timestamp":1776822308000},"page":"634-648","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative Blood Transfusion and Mortality After Pancreatic Surgery: A Nationwide Cohort Study With Propensity Score Matching"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3323-6405","authenticated-orcid":false,"given":"Seonghae","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Health Statistics, Graduate School of Public Health Hanyang University  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8105-9861","authenticated-orcid":false,"given":"Sunghee","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Statistics and Data Science, Graduate School Dongguk University  Seoul Korea"},{"name":"Institute for Health and Society Hanyang University  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9979-9910","authenticated-orcid":false,"given":"Seonju","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences Hanyang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0356-6037","authenticated-orcid":false,"given":"Junghyun","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Hanyang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5193-5418","authenticated-orcid":false,"given":"Yun Kyung","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Surgery Hanyang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3275-3544","authenticated-orcid":false,"given":"Kyeong Geun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery Hanyang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1255-1964","authenticated-orcid":false,"given":"Dongho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Surgery Hanyang University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1902-3184","authenticated-orcid":false,"given":"Boyoung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Hanyang University College of Medicine  Seoul Korea"},{"name":"Hanyang Institute of Bioscience and Biotechnology Hanyang University  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.05.020"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2025.108.1.20"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znad330"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0259682"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010015\u20104823\u20106"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.21037\/apc\u201021\u201011"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2018.10.018"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9030689"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2023.08.032"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000001825"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40140\u2010016\u20100174\u20105"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/00273171.2011.568786"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2025.40.e111"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009019"},{"issue":"4","key":"e_1_2_11_16_1","first-page":"188","article-title":"Charlson Comorbidity Index: ICD\u20109 Update and ICD\u201010 Translation","volume":"12","author":"Glasheen W. 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