{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T06:56:31Z","timestamp":1772002591918,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T00:00:00Z","timestamp":1585872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study was designed to analyze the risk of extra\u2010anatomical portal vein reconstruction during liver transplantation (LT) in patient with portal vein thrombosis (PVT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent LT between 2008 and 2018 were reviewed. PVT was graded according to the Yerdel system. Risk factor for portal vein complication\u2010free, graft and overall survival were analyzed with multivariate Cox regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy out of 1180 patients had PVT. Number of patients who underwent extra\u2010anatomical reconstruction were three (13.0%), three (15.0%), and six (50.0%) with grade II, III and IV thrombosis, respectively. Grade III patients with extra\u2010anatomical reconstruction (HR\u00a010.212, CI\u00a02.475\u201042.133, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001), grade IV with both anatomical (HR\u00a016.991, CI\u00a05.224\u201054.740, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) and extra\u2010anatomical reconstruction (HR\u00a012.262, CI\u00a02.698\u201050.666, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001) were risk factors for portal vein complication\u2010free survival. Grade IV thrombosis with both anatomical (HR\u00a04.296, CI\u00a01.059\u201017.430, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.041) and extra\u2010anatomical reconstruction (HR\u00a07.777, CI\u00a02.461\u201024.571, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) were risk factors for graft failure. Extra\u2010anatomical reconstruction for both grade I to III (HR\u00a03.638, CI\u00a01.155\u201011.453, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.027) and grade IV thrombosis (HR\u00a04.798, CI\u00a01.773\u201012.982, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.002) were risk factors for survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Grade IV thrombosis and extra\u2010anatomical reconstruction were related to poor prognosis. Therefore, thorough evaluation and planning is required for these patients to improve the outcome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.711","type":"journal-article","created":{"date-parts":[[2020,1,16]],"date-time":"2020-01-16T18:39:42Z","timestamp":1579199982000},"page":"242-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Portal vein thrombosis during liver transplantation: The risk of extra\u2010anatomical portal vein reconstruction"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9809-8525","authenticated-orcid":false,"given":"Jinsoo","family":"Rhu","sequence":"first","affiliation":[{"name":"Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyu\u2010Seong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choon Hyuck David","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of General Surgery Digestive Disease and Surgery Institute Lerner College of Medicine Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Man","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae\u2010Won","family":"Joh","sequence":"additional","affiliation":[{"name":"Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000252"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2010.01217.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.235"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318206818b"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01649.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12803"},{"key":"e_1_2_7_8_1","first-page":"1146","article-title":"Gore\u2010Tex jump graft for portal vein thrombosis following living donor liver transplantation","volume":"50","author":"Hashimoto 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