{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:25:38Z","timestamp":1761920738456,"version":"3.40.5"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T00:00:00Z","timestamp":1592697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We assessed the usefulness of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid enhanced magnetic resonance imaging for the prediction of posthepatectomy liver failure (PHLF) after a major hepatectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed 140 cases involving a hepatectomy of two or more sections between 2010 and 2016 (study cohort). We used the standardized remnant hepatocellular uptake index (SrHUI) which was calculated by: SrHUI\u00a0=\u00a0future remnant liver volume\u00a0\u00d7\u00a0[(signal intensity of remnant liver on hepatobiliary phase images\/signal intensity of spleen on hepatobiliary phase images)\u00a0\u2212\u00a01]\/body surface area. Validation of the SrHUI was performed in another cohort of 52 major hepatectomy cases between 2017 and 2018 (validation cohort).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The SrHUI of patients with PHLF was significantly lower than that of non\u2010PHLF cases. Receiver operating characteristic analysis and the Youden index revealed that the SrHUI cutoff value for the prediction of PHLF and PHLF grade\u00a0\u2265\u00a0B were 0.313\u00a0L\/m<jats:sup>2<\/jats:sup> and 0.257\u00a0L\/m<jats:sup>2<\/jats:sup>, respectively. In the validation cohort, the cutoff value of SrHUI for the prediction of PHLF or PHLF grade\u00a0\u2265\u00a0B had a sensitivity of 75.0% or 88.8%, and specificity of 78.1% or 91.6%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The SrHUI value is a predictor for PHLF after a major hepatectomy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.769","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T07:02:00Z","timestamp":1590994920000},"page":"531-540","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Predictive value of gadoxetic acid enhanced magnetic resonance imaging for posthepatectomy liver failure after a major hepatectomy"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4398-0697","authenticated-orcid":false,"given":"Tatsuya","family":"Orimo","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiya","family":"Kamiyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirofumi","family":"Kamachi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihisa","family":"Nagatsu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoh","family":"Asahi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzuru","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Abo","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Hokkaido University Hospital Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinobu","family":"Taketomi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery I Hokkaido University Graduate School of Medicine Sapporo 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