{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T22:26:43Z","timestamp":1776378403774,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,11,29]],"date-time":"2020-11-29T00:00:00Z","timestamp":1606608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Hepato Biliary Pancreat"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate a risk\u2010adjusted comparison of clinically relevant postoperative pancreatic fistula POPF (CR\u2010POPF) following laparoscopic pancreatoduodenectomy (LPD) vs open pancreatoduodenectomy (OPD) using the fistula risk score (FRS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed 579 patients who underwent LPD (n\u00a0=\u00a0274) or OPD (n\u00a0=\u00a0305) between 2012 and 2019 at two tertiary hospitals. Using the FRS, the risk was stratified into four categories; negligible, low, intermediate and high risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median FRS was significantly higher in the LPD than in the OPD group (5.4\u00a0\u00b1\u00a01.2 vs 3.9\u00a0\u00b1\u00a01.8, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). The overall incidence of CR\u2010POPF in the LPD vs OPD groups were 16.4% vs 17.7% (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.187). When POPF risks were stratified by FRS, CR\u2010POPF following LPD vs OPD in patients with low risk (0% vs 6.3%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.294), intermediate risk (16.1% vs 22.9%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.053) and high risk (33.3% vs 27.3%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.577) were not significantly different.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite a higher risk score in the LPD group, the CR\u2010POPF was similar following both procedures in the unadjusted and FRS\u2010risk\u2010adjusted comparisons. The CR\u2010POPF was more significantly affected by patient risk factors such as the soft pancreas and small pancreatic duct.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhbp.866","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T08:21:26Z","timestamp":1605082886000},"page":"1089-1097","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Fistula risk score\u2010adjusted comparison of postoperative pancreatic fistula following laparoscopic vs open pancreatoduodenectomy"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1567-1774","authenticated-orcid":false,"given":"Boram","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Surgery Seoul National University Bundang Hospital Seoul National University College of Medicine Seongnam\u2010si 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