{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:25:43Z","timestamp":1760660743844,"version":"build-2065373602"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["shmpublications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Examine baseline factors associated with a new diagnosis of opioid use disorder (OUD) within 12 months postdischarge among opioid\u2010na\u00efve patients who received an opioid prescription in the inpatient setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design\/Setting<\/jats:title><jats:p>Retrospective cohort (surgery and nonsurgery) study of opioid\u2010naive patients who had at least one prescription for an opioid during an inpatient hospitalist between 2014 and 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Twenty\u2010three thousand and thirty\u2010three patients were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The primary objective was to determine baseline factors associated with a new OUD diagnosis within 12 months of discharge. Baseline covariates included demographic information, clinical characteristics, medication use, characteristics related to index hospital encounter, and discharge location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>2.1% of the sample had a new diagnosis of OUD within a year after receiving an opioid during hospital admission. Patients between ages 25 and 34 had higher odds of a new OUD diagnosis compared to those 65 years of age and older (odds ratio [OR]: 6.98, 95% confidence interval [CI]: 4.02\u201312.1 [nonsurgery] and 4.69, 95% CI: 2.63\u20138.37 [surgery]). Patients from a high opioid geo\u2010rank region had higher odds of OUD diagnosis (OR: 2.08, 95% CI: 1.31\u20133.31 [nonsurgery] and 1.80, 95% CI: 1.03\u20133.15 [surgery]). History of nonopioid\u2010related drug disorder, tobacco use disorder, mental health conditions, and gabapentin use 12 months prior to index date and white race were associated with higher odds of new OUD diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It is important to identify and evaluate factors associated with developing a new diagnosis of OUD following hospitalization. This can inform pain management strategies within the hospital and at discharge, and prompt clinicians to screen for risk of OUD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhm.12835","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T03:13:25Z","timestamp":1652670805000},"page":"342-349","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Patient and medication\u2010related factors associated with opioid use disorder after inpatient opioid administration"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8938-4236","authenticated-orcid":false,"given":"Elizabeth C.S.","family":"Swart","sequence":"first","affiliation":[{"name":"UPMC Centers for High\u2010Value Health Care and Value\u2010Based Pharmacy Initiatives UPMC Health Plan  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terri V.","family":"Newman","sequence":"additional","affiliation":[{"name":"Department of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Huang","sequence":"additional","affiliation":[{"name":"UPMC Centers for High\u2010Value Health Care and Value\u2010Based Pharmacy Initiatives UPMC Health Plan  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8766-5544","authenticated-orcid":false,"given":"Robert J.","family":"Howell","sequence":"additional","affiliation":[{"name":"Department of Health Economics UPMC Health Plan Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Health Economics UPMC Health Plan Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4388-4558","authenticated-orcid":false,"given":"Chester B.","family":"Good","sequence":"additional","affiliation":[{"name":"UPMC Centers for High\u2010Value Health Care and Value\u2010Based Pharmacy Initiatives UPMC Health Plan  Pittsburgh Pennsylvania USA"},{"name":"Division of General Internal Medicine University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel K.","family":"Peasah","sequence":"additional","affiliation":[{"name":"UPMC Centers for High\u2010Value Health Care and Value\u2010Based Pharmacy Initiatives UPMC Health Plan  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4467-8473","authenticated-orcid":false,"given":"Natasha","family":"Parekh","sequence":"additional","affiliation":[{"name":"John A. 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