{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:47:46Z","timestamp":1786978066706,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["shmpublications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Opioid and benzodiazepine prescribing after COVID\u201019 hospitalization is not well understood. We aimed to characterize opioid and benzodiazepine prescribing among na\u00efve patients hospitalized for COVID and to identify the risk factors associated with a new prescription at discharge. In this retrospective study of patients across 39 Michigan hospitals from March to November 2020, we identified 857 opioid\u2010 and benzodiazepine\u2010na\u00efve patients admitted with COVID\u201019 not requiring mechanical ventilation. Of these, 22% received opioids, 13% received benzodiazepines, and 6% received both during the hospitalization. At discharge, 8% received an opioid prescription, and 3% received a benzodiazepine prescription. After multivariable adjustment, receipt of an opioid or benzodiazepine prescription at discharge was associated with the length of inpatient opioid or benzodiazepine exposure. These findings suggest that hospitalization represents a risk of opioid or benzodiazepine initiation among na\u00efve patients, and judicious prescribing should be considered to prevent opioid\u2010related harms.<\/jats:p>","DOI":"10.1002\/jhm.12842","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T05:14:28Z","timestamp":1653628468000},"page":"539-544","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Opioid and benzodiazepine prescribing after COVID\u201019 hospitalization"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6573-0774","authenticated-orcid":false,"given":"Lia D.","family":"Delaney","sequence":"first","affiliation":[{"name":"University of Michigan Medical School Ann Arbor Michigan USA"},{"name":"Center for Healthcare Outcomes and Policy Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9406-5953","authenticated-orcid":false,"given":"Mark C.","family":"Bicket","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Michigan Health System Ann Arbor Michigan USA"},{"name":"Michigan Opioid Prescribing Engagement Network Institute for Healthcare Policy and Innovation Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsou Mei","family":"Hu","sequence":"additional","affiliation":[{"name":"Michigan Opioid Prescribing Engagement Network Institute for Healthcare Policy and Innovation Ann Arbor MI"},{"name":"Department of Surgery University of Michigan Health System Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"O'Malley","sequence":"additional","affiliation":[{"name":"The Division of Hospital Medicine, Department of Internal Medicine University of Michigan Health System Ann Arbor Michigan USA"},{"name":"The Hospital Medicine Safety Consortium Coordinating Center Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"McLaughlin","sequence":"additional","affiliation":[{"name":"The Division of Hospital Medicine, Department of Internal Medicine University of Michigan Health System Ann Arbor Michigan USA"},{"name":"The Hospital Medicine Safety Consortium Coordinating Center Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A.","family":"Flanders","sequence":"additional","affiliation":[{"name":"The Division of Hospital Medicine, Department of Internal Medicine University of Michigan Health System Ann Arbor Michigan USA"},{"name":"The Hospital Medicine Safety Consortium Coordinating Center Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie M.","family":"Vaughn","sequence":"additional","affiliation":[{"name":"The Division of Hospital Medicine, Department of Internal Medicine University of Michigan Health System Ann Arbor Michigan USA"},{"name":"Division of General Internal Medicine, Department of Internal Medicine University of Utah Salt Lake City Utah USA"},{"name":"Division of Health System Innovation &amp; Research University of Utah Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer F.","family":"Waljee","sequence":"additional","affiliation":[{"name":"Center for Healthcare Outcomes and Policy Ann Arbor Michigan USA"},{"name":"Michigan Opioid Prescribing Engagement Network Institute for Healthcare Policy and Innovation Ann Arbor MI"},{"name":"Department of Surgery University of Michigan Health System Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-015-3539-4"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.0504"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2016.2737"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/10600280211016856"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-018-4335-8"},{"key":"e_1_2_8_7_1","unstructured":"Centers for Disease Control and Prevention. CDC COVID Data Tracker. United States COVID\u201019 cases and deaths by state.https:\/\/covid.cdc.gov\/covid-data-tracker\/#datatracker-home. Published 2021. Accessed July 15 2021."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216320949786"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2020.12.014"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M20-5661"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.3721"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2018.04.043"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.2979"},{"key":"e_1_2_8_14_1","doi-asserted-by":"crossref","unstructured":"McKeiguePM KennedyS WeirA et al.Associations of severe COVID\u201019 with polypharmacy in the REACT\u2010SCOT case\u2010control study.medRxiv. 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Accessed March 4 2021.https:\/\/www.modernhealthcare.com\/article\/20171211\/NEWS\/171219988\/blue-cross-to-limit-opioid-scripts-to-30-day-supply"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2018.4234"}],"container-title":["Journal of Hospital Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jhm.12842","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jhm.12842","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/shmpublications.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jhm.12842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:22:49Z","timestamp":1760628169000},"score":1,"resource":{"primary":{"URL":"https:\/\/shmpublications.onlinelibrary.wiley.com\/doi\/10.1002\/jhm.12842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,27]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1002\/jhm.12842"],"URL":"https:\/\/doi.org\/10.1002\/jhm.12842","archive":["Portico"],"relation":{},"ISSN":["1553-5592","1553-5606"],"issn-type":[{"value":"1553-5592","type":"print"},{"value":"1553-5606","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,27]]},"assertion":[{"value":"2021-10-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}