{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:13:28Z","timestamp":1792293208383,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T00:00:00Z","timestamp":1402272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Peripherally inserted central catheters (PICCs) are increasingly utilized. Patient and system factors that increase risk of complications should be identified to avoid preventable patient harm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A case control analysis of adult inpatients who underwent PICC placement from January 2009 to January 2010 at Scott &amp; White Memorial Hospital was conducted to determine the incidence and risk factors for complications. One hundred seventy cases of inpatients who experienced PICC\u2010related complications were identified. Age\u2010 and gender\u2010matched controls were randomly selected among patients who underwent PICC placement without documented complications during this time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 1444 PICCs were placed, with a complication rate of 11.77% (95% confidence interval: 10.11%\u201013.44%). Complications included catheter\u2010associated thrombosis (3%), mechanical complications (4%), catheter\u2010associated bloodstream infections (2%), and cellulitis (1%). In multivariable logistic regression analyses, malnutrition and after\u2010hours placement were significantly associated with increased risk of complications, as was body mass index (BMI) &gt;30 after adjusting for anticoagulation and time of placement. In a secondary multivariable logistic regression analysis, after\u2010hours placement and malnutrition were significantly associated with increased risk of nonmechanical complications. Additionally, in conditional univariate analyses, length of stay, malnutrition, and after\u2010hours placement were associated with increased risk of catheter\u2010associated thrombosis. In our multivariable logistic regression analyses, use of anticoagulation\/antiplatelet agents was associated with decreased risk of all\u2010cause complications, nonmechanical complications, and catheter\u2010associated thrombosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>\n                      Screening of patients undergoing PICC placement with attention to malnutrition, BMI &gt;30, and length of stay may reduce the risk of PICC\u2010associated complications. Use of anticoagulation\/antiplatelet agents and avoiding after\u2010hours placement may reduce complications and enhance patient safety.\n                      <jats:italic>Journal of Hospital Medicine<\/jats:italic>\n                      2014;9:481\u2013489. \u00a9 2014 Society of Hospital Medicine\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhm.2207","type":"journal-article","created":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T06:37:36Z","timestamp":1402295856000},"page":"481-489","source":"Crossref","is-referenced-by-count":30,"title":["Screening for novel risk factors related to peripherally inserted central catheter\u2010associated complications"],"prefix":"10.1002","volume":"9","author":[{"given":"Jennifer","family":"Moran","sequence":"first","affiliation":[{"name":"Department of Medicine Baylor Scott &amp; White Health Temple Texas"},{"name":"Texas A &amp; M University System Health Science Center College of Medicine College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen Y.","family":"Colbert","sequence":"additional","affiliation":[{"name":"Texas A &amp; 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