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Recent data show that CCBs are the most common of the cardiovascular medications noted in intentional or unintentional overdoses.<jats:sup>1<\/jats:sup> Novel treatment approaches in the form of glucagon, high\u2010dose insulin therapy, and intravenous lipid emulsion therapies have been tried and have been successful. However, the evidence for these are limited to case reports and case series. We take this opportunity to review the various treatment options in the management of CCB overdoses with a special focus on high\u2010dose insulin therapy as the emerging choice for initial therapy in severe overdoses. <jats:italic>Journal of Hospital Medicine<\/jats:italic> 2014;9:663\u2013668. \u00a9 2014 Society of Hospital Medicine<\/jats:p>","DOI":"10.1002\/jhm.2241","type":"journal-article","created":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T06:46:37Z","timestamp":1406529997000},"page":"663-668","source":"Crossref","is-referenced-by-count":10,"title":["Management of calcium channel blocker overdoses"],"prefix":"10.1002","volume":"9","author":[{"given":"Sundeep","family":"Shenoy","sequence":"first","affiliation":[{"name":"Division of Inpatient Medicine University of Arizona Tucson Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpa","family":"Lankala","sequence":"additional","affiliation":[{"name":"Division of Hospital Medicine Banner Good 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