{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T08:47:57Z","timestamp":1768985277448,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p><jats:italic>Staphylococcus aureus<\/jats:italic> bacteremia (SAB) is associated with significant morbidity and mortality in hospitalized adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>We aimed to identify current practice patterns in the management of SAB, and to evaluate their association with clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>DESIGN<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>SETTING<\/jats:title><jats:p>A 1558\u2010bed tertiary care teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS<\/jats:title><jats:p>Adult patients hospitalized between January 1, 2012 through April 30, 2013, who had at least 1 positive blood culture with <jats:italic>S aureus<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>INTERVENTION<\/jats:title><jats:p>None<\/jats:p><\/jats:sec><jats:sec><jats:title>MEASUREMENTS<\/jats:title><jats:p>Electronic medical records were reviewed and the processes of care in the management of SAB were identified. The main outcome was clinical failure, defined as a composite endpoint of in\u2010hospital mortality and persistent bacteremia.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Two hundred fifty episodes of SAB occurred in 241 patients, and 78 (32.4%) had clinical failure. Processes of care that impacted the risk of clinical failure included: timing of follow\u2010up blood cultures (delays of &gt;4 days had a relative risk [RR] of 6.6; 95% confidence interval [CI]: 2.1\u201320.5; <jats:italic>P<\/jats:italic>\u2009=\u20090.001), consultation with infectious diseases specialist within 6 days from diagnosis of SAB (RR: 0.3; 95% CI: 0.1\u22120.9; <jats:italic>P<\/jats:italic>\u2009=\u20090.03), and use of \u03b2\u2010lactams in patients with methicillin\u2010susceptible <jats:italic>S aureus<\/jats:italic> bacteremia (RR: 0.1; 95% CI: 0.04\u22120.5; <jats:italic>P<\/jats:italic>\u2009=\u20090.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The processes of care identified in our study could serve as quality and patient safety indicators for the management of SAB. <jats:italic>Journal of Hospital Medicine<\/jats:italic> 2016;11:27\u201332. \u00a9 2015 Society of Hospital Medicine<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhm.2479","type":"journal-article","created":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T05:45:44Z","timestamp":1442555144000},"page":"27-32","source":"Crossref","is-referenced-by-count":6,"title":["Performance of processes of care and outcomes in patients with <scp><i>S<\/i><\/scp><i>taphylococcus aureus<\/i> bacteremia"],"prefix":"10.1002","volume":"11","author":[{"given":"Rossana","family":"Rosa","sequence":"first","affiliation":[{"name":"Department of Medicine Jackson Memorial Hospital Miami Florida"},{"name":"Department of Medicine Division of Infectious Diseases University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Wawrzyniak","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maroun","family":"Sfeir","sequence":"additional","affiliation":[{"name":"Department of Medicine Jackson Memorial Hospital Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Jackson Memorial Hospital Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilian M.","family":"Abbo","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Infectious Diseases University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/421946"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-0711-5-2"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/502522"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-69-5-859"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/345476"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/inf.1985.17.issue-2.09"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.15.1756"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.9763"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciq146"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/529190"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1086\/514686"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/IPC.0b013e318255d67c"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.01.015"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit499"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1086\/677624"},{"key":"e_1_2_6_17_1","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing; 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