{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:22:49Z","timestamp":1760660569107,"version":"build-2065373602"},"reference-count":38,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T00:00:00Z","timestamp":1742428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["shmpublications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Low\u2010trauma fractures of the hip signify osteoporosis and increase the risk of a second fracture. However, screening for secondary osteoporosis and initiating osteoporosis treatment can be challenging in a geriatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate an in\u2010hospital approach to secure treatment, screening and follow\u2010up of osteoporosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated the feasibility of a clinical approach to osteoporosis treatment with in\u2010hospital zoledronic acid (ZOL) infusion, screening for secondary osteoporosis, and dual\u2010energy X\u2010ray absorptiometry (DXA) with a vertebral fracture assessment (VFA) in a cohort of 128 patients. We compared this cohort to a historic cohort of 135 patients, where screening and treatment were provided by general practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the intervention cohort, 58% of the patients received anti\u2010osteoporosis treatment within 6 months of admission. Forty\u2010eight patients (38%) received ZOL during admission, while nine continued their usual treatment. An additional 17 patients received ZOL or another anti\u2010osteoporosis treatment within 6 months. The most common reasons for <jats:italic>not<\/jats:italic> receiving ZOL were vitamin D deficiency (24%) and renal impairment (7%). In total, 35% (<jats:italic>n<\/jats:italic>\u2009=\u200943) had a DXA within 6 months of admission; VFA revealed nine cases of vertebral fractures. Screening for secondary osteoporosis revealed vitamin D deficiency with and without secondary hyperparathyroidism (48%) and subclinical hyperthyroidism (8%) as the most common findings. Together, biochemical screening and VFA changed the treatment strategy in less than five cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Administering ZOL in\u2010hospital following a hip fracture in combination with a systematic follow\u2010up secured treatment in 6 out of 10 patients. However, compliance with DXA was low, which might not be of major concern, since DXA only individualized treatment in a few patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jhm.70036","type":"journal-article","created":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T03:26:23Z","timestamp":1742700383000},"page":"935-942","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Systematic in\u2010hospital screening and treatment for osteoporosis in a geriatric population with hip fractures"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7863-0016","authenticated-orcid":false,"given":"Jeppe B.","family":"Rosenb\u00e6k","sequence":"first","affiliation":[{"name":"Department of Internal Medicine G\u00f8dstrup Hospital Herning Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7676-5323","authenticated-orcid":false,"given":"Line B.","family":"Dalgaard","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine G\u00f8dstrup Hospital Herning Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7440-6309","authenticated-orcid":false,"given":"Anne","family":"Grauballe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine G\u00f8dstrup Hospital Herning Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stella J.","family":"Wilfred","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine G\u00f8dstrup Hospital Herning Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikkel W.","family":"Ibsen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine G\u00f8dstrup Hospital Herning Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8964-9564","authenticated-orcid":false,"given":"Lene R.","family":"Madsen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine G\u00f8dstrup Hospital Herning Denmark"},{"name":"Steno Diabetes Center Aarhus, Aarhus University Hospital Aarhus Denmark"},{"name":"Danish Diabetes Academy, Odense University Hospital Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2655-z"},{"issue":"1","key":"e_1_2_9_3_1","first-page":"105","article-title":"The epidemiology of osteoporosis","volume":"133","author":"Clynes MA","year":"2020","journal-title":"Br Med Bull"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2014.51"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4821"},{"key":"e_1_2_9_6_1","unstructured":"Dansk Tv\u00e6rfagligt Register for Hoften\u00e6re L\u00e5rbensbrud Regionernes Kliniske Kvalitetsudviklingsprogram. 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