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With over 100 serotypes, it can cause a wide spectrum of illness ranging from acute otitis media and sinusitis to life\u2010threatening manifestations such as bacteremia, pneumonia, and meningitis. Pneumococcal vaccines target a subset of these serotypes, and the introduction of the pneumococcal conjugate vaccine in 2000 led to dramatic declines in the rate of colonization, transmission, and disease incidence across all populations. Hospitalists play a crucial role in treating patients with pneumococcal disease and identifying vaccine\u2010eligible patients.\n                  <\/jats:p>","DOI":"10.1002\/jhm.70105","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:35:13Z","timestamp":1750293313000},"page":"1217-1222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical progress note: Pneumococcal disease"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3424-9771","authenticated-orcid":false,"given":"Elizabeth L.","family":"Nguyen","sequence":"first","affiliation":[{"name":"Division of Pediatric Hospital Medicine Stanford University School of Medicine Palo Alto California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preeti","family":"Mehrotra","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Beth Israel Deaconess Medical Center and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9216-2650","authenticated-orcid":false,"given":"Marie E.","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hospital Medicine Stanford University School of Medicine Palo Alto California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"CDC. 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