{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:27:51Z","timestamp":1773001671569,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:00Z","timestamp":1761264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:00Z","timestamp":1761264000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["1K08HS029693"],"award-info":[{"award-number":["1K08HS029693"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["shmpublications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We evaluated whether peripheral intravenous catheter (PIV) utilization and complications (i.e., infiltration\/extravasation) differed between children hospitalized with pneumonia who received initial oral versus intravenous antibiotics. In a retrospective cohort study of children hospitalized with pneumonia at four affiliated sites within a single hospital system from 2014 to 2020, we evaluated PIV outcomes and compared them using bivariable analyses and multivariable regression models. Among 1035 children, 65% received initial oral antibiotics and 59% had PIVs. PIVs were placed in 38% of children with oral antibiotics and 99% with IV antibiotics. Infiltration\/extravasation occurred in 1% of children with oral antibiotics and 9% with IV antibiotics. Among children with PIVs, those with oral antibiotics had lower odds of infiltration\/extravasation (odds ratio [OR]: 0.39, 95% confidence interval [CI]: 0.17\u20130.9). Given the pain and anxiety of PIVs for children and the morbidity associated with infiltrations\/extravasations, initial oral antibiotics provide an opportunity to improve patient and family experiences and minimize PIV\u2010related harms.<\/jats:p>","DOI":"10.1002\/jhm.70225","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T12:02:41Z","timestamp":1761307361000},"page":"284-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intravenous line\u2010related outcomes by antibiotic route for children hospitalized with pneumonia"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7978-9045","authenticated-orcid":false,"given":"Jillian M.","family":"Cotter","sequence":"first","affiliation":[{"name":"Section of Hospital Medicine, Department of Pediatrics, Children\u2032s Hospital Colorado University of Colorado Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Dunn","sequence":"additional","affiliation":[{"name":"Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) University of Colorado School of Medicine and Children\u2032s Hospital Colorado Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Zaniletti","sequence":"additional","affiliation":[{"name":"Children\u2032s Hospital Association Lenexa Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Colborn","sequence":"additional","affiliation":[{"name":"Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) University of Colorado School of Medicine and Children\u2032s Hospital Colorado Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0295-1240","authenticated-orcid":false,"given":"Derek J.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hospital Medicine Monroe Carell Jr Children\u2032s Hospital at VUMC Vanderbilt University School of Medicine Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1389-5726","authenticated-orcid":false,"given":"Sriram","family":"Ramgopal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Emergency Medicine, Ann &amp; Robert H. Lurie Children\u2032s Hospital of Chicago Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5587-730X","authenticated-orcid":false,"given":"Cristin Q.","family":"Fritz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hospital Medicine Monroe Carell Jr Children\u2032s Hospital at VUMC Vanderbilt University School of Medicine Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4976-969X","authenticated-orcid":false,"given":"Maia","family":"Taft","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Pittsburgh School of Medicine Pittsburgh Pennsylvania 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Colorado School of Medicine and Children\u2032s Hospital Colorado Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilliam","family":"Ambroggio","sequence":"additional","affiliation":[{"name":"Sections of Hospital Medicine and Emergency Medicine, Children\u2032s Hospital Colorado and Department of Pediatrics University of Colorado Aurora Colorado 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