{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T06:12:47Z","timestamp":1788329567381,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["shmpublications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Medicine"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Central venous access devices (CVADs) are frequently used in Hospital\u2010At\u2010Home models to facilitate prolonged intravenous treatment for children. Premature CVAD dressing disruption is common and contributes to device failure. This protocol describes a trial evaluating the adjunctive use of medical liquid adhesive at the dressing\u2013skin interface to improve dressing adhesion and maintain dressing integrity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010site, two\u2010arm, parallel\u2010group, superiority randomized controlled trial undertaken in a children's Hospital\u2010at\u2010Home will evaluate whether adding medical liquid adhesive to standard CVAD dressings, compared with standard dressing alone, reduces dressing disruption. Children aged \u226418 years requiring a CVAD for \u22657 days will be randomized 1:1 to standard dressing plus medical liquid adhesive or standard dressing alone. Dressing integrity will be assessed daily, with dressing\u2010related outcomes assessed after 7 days or following dressing change (whichever occurs first). At each dressing change, participants are eligible for repeat participation, retaining their original randomization. The primary outcome is dressing disruption requiring premature replacement or reinforcement before the scheduled 7\u2010day change. Secondary dressing\u2010related outcomes include dressing dwell\u2010time, skin adverse events, CVAD complications, patient, caregiver, and clinician satisfaction. Secondary outcomes assessed once per participant are healthcare utilization and costs. Analyses will follow the intention\u2010to\u2010treat principle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Ensuring the safety and durability of invasive devices beyond the in\u2010hospital setting is an increasing priority in pediatric care. This trial will provide rigorous data to inform the clinical\u2010 and cost\u2010effectiveness of the addition of medical liquid adhesive to standard dressings to improve CVAD dressing integrity, supporting care across the hospital\u2010to\u2010home continuum.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jhm.70376","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T14:52:52Z","timestamp":1784213572000},"page":"1089-1099","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric home\u2010based central venous access device dressings: Medical liquid adhesive versus standard care to reduce dressing disruption: The STICKY\u2010kids RCT protocol"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8369-3970","authenticated-orcid":false,"given":"Tricia M.","family":"Kleidon","sequence":"first","affiliation":[{"name":"Queensland Children's Hospital, Children's Health Queensland Hospital and Health Service South Brisbane Queensland Australia"},{"name":"School of Nursing, Midwifery and Social Work, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland, St Lucia  Queensland Australia"},{"name":"School of Nursing and Midwifery, Alliance for Vascular Access Teaching and Research (AVATAR) Griffith University Nathan Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1167-9106","authenticated-orcid":false,"given":"Mari","family":"Takashima","sequence":"additional","affiliation":[{"name":"Queensland Children's Hospital, Children's Health Queensland Hospital and Health Service South Brisbane Queensland Australia"},{"name":"School of Nursing, Midwifery and Social Work, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland, St Lucia  Queensland Australia"},{"name":"Griffith Biostatistical Unit Griffith University Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6129-6736","authenticated-orcid":false,"given":"Robert S.","family":"Ware","sequence":"additional","affiliation":[{"name":"Griffith Biostatistical Unit Griffith University Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5779-1304","authenticated-orcid":false,"given":"R. N.","family":"Nicole Marsh","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Alliance for Vascular Access Teaching and Research (AVATAR) Griffith University Nathan Queensland Australia"},{"name":"Nursing and Midwifery Research Centre Royal Brisbane, and Women's Hospital Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8860-5319","authenticated-orcid":false,"given":"Amanda J","family":"Ullman","sequence":"additional","affiliation":[{"name":"Queensland Children's Hospital, Children's Health Queensland Hospital and Health Service South Brisbane Queensland Australia"},{"name":"School of Nursing, Midwifery and Social Work, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland, St Lucia  Queensland Australia"},{"name":"School of Nursing and Midwifery, Alliance for Vascular Access Teaching and Research (AVATAR) Griffith University Nathan Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2019-3474I"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.14600"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000532"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2017.07.012"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1043454219849572"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31824e0d46"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/NOR.0b013e3182a39caf"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2023.104620"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2024.2202"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2016-218757"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2024.0485"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10638"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30345-6"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.15209"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24670"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2023.0294"},{"issue":"6","key":"e_1_2_8_18_1","first-page":"8","article-title":"Infusion therapy: a model for safe practice in the home setting","volume":"15","author":"Gorski LA","year":"2020","journal-title":"Am Nurse Today"},{"key":"e_1_2_8_19_1","unstructured":"About Home and Alternate Site Infusion. 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