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Vaccines have profoundly affected the natural history of influenza to become our most effective means of prevention. In these times of increasing vaccine hesitancy, there is a need for an ongoing strong endorsement of the annual influenza vaccine to prevent severe illness, reduce hospitalizations\/deaths, protect vulnerable populations, and minimize community spread.<\/jats:p>","DOI":"10.1002\/jhm.70381","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T14:17:20Z","timestamp":1782915440000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical progress note: Influenza"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6358-3424","authenticated-orcid":false,"given":"Feargal A.","family":"Donaghy","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth P.","family":"Schlaudecker","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"1205","volume-title":"Principles and Practice of Pediatric Infectious Diseases","author":"Long SS","year":"2023"},{"issue":"7","key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.3390\/ijms18071541","article-title":"The interplay between the host receptor and influenza virus hemagglutinin and neuraminidase","volume":"18","author":"Byrd\u2010Leotis L","year":"2017","journal-title":"Int J Mol Sci"},{"issue":"10","key":"e_1_2_5_4_1","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1093\/cid\/cix1060","article-title":"Seasonal incidence of symptomatic influenza in the United States","volume":"66","author":"Tokars JI","year":"2018","journal-title":"Clin Infect Dis"},{"issue":"6","key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss7706a1","article-title":"Laboratory\u2010confirmed influenza\u2010associated hospitalizations among children and adults\u2014Influenza Hospitalization Surveillance Network, United States, 2010\u20102023","volume":"73","author":"Naquin A","year":"2024","journal-title":"MMWR Surveill Summ"},{"key":"e_1_2_5_6_1","unstructured":"CDC Yellow Book 2026: Influenza.2026. 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