{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:27:40Z","timestamp":1792301260586,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T00:00:00Z","timestamp":1519689600000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000279","name":"Nuffield Foundation","doi-asserted-by":"publisher","award":["CPF\/41513"],"award-info":[{"award-number":["CPF\/41513"]}],"id":[{"id":"10.13039\/501100000279","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","award":["IAA\u2010MT13\u2010 003"],"award-info":[{"award-number":["IAA\u2010MT13\u2010 003"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["FP7\/2007\u20102013"],"award-info":[{"award-number":["FP7\/2007\u20102013"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Intern AIDS Soc"],"published-print":{"date-parts":[[2018,2]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n \n The Sustainable Development Goals (\n SDG<\/jats:styled-content>\n s) present a groundbreaking global development agenda to protect the most vulnerable. Adolescents living with\n HIV<\/jats:styled-content>\n in Sub\u2010Saharan Africa continue to experience extreme health vulnerabilities, but we know little about the impacts of\n SDG<\/jats:styled-content>\n \u2010aligned provisions on their health. This study tests associations of provisions aligned with five\n SDG<\/jats:styled-content>\n s with potential mortality risks.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Clinical and interview data were gathered from N\u00a0=\u00a01060 adolescents living with\n HIV<\/jats:styled-content>\n in rural and urban South Africa in 2014 to 2015. All\n ART<\/jats:styled-content>\n \u2010initiated adolescents from 53 government health facilities were identified, and traced in their communities to include those defaulting and lost\u2010to\u2010follow\u2010up. Potential mortality risk was assessed as either: viral suppression failure (1000+ copies\/ml) using patient file records, or adolescent self\u2010report of diagnosed but untreated tuberculosis or symptomatic pulmonary tuberculosis.\n SDG<\/jats:styled-content>\n \u2010aligned provisions were measured through adolescent interviews. Provisions aligned with\n SDG<\/jats:styled-content>\n s 1&2 (no poverty and zero hunger) were operationalized as access to basic necessities, social protection and food security; An\n SDG<\/jats:styled-content>\n 3\u2010aligned provision (\n ensure healthy lives<\/jats:italic>\n ) was having a healthy primary caregiver; An\n SDG<\/jats:styled-content>\n 8\u2010aligned provision (\n employment for all<\/jats:italic>\n ) was employment of a household member; An\n SDG<\/jats:styled-content>\n 16\u2010aligned provision (\n protection from violence<\/jats:italic>\n ) was protection from physical, sexual or emotional abuse. Research partners included the South African national government,\n UNICEF<\/jats:styled-content>\n and Pediatric and Adolescent Treatment for Africa.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n 20.8% of adolescents living with\n HIV<\/jats:styled-content>\n had potential mortality risk \u2013 i.e. viral suppression failure, symptomatic untreated\n TB<\/jats:styled-content>\n , or both. All\n SDG<\/jats:styled-content>\n \u2010aligned provisions were significantly associated with reduced potential mortality risk:\n SDG<\/jats:styled-content>\n 1&2 (\n OR<\/jats:styled-content>\n 0.599\n CI<\/jats:styled-content>\n 0.361 to 0.994);\n SDG<\/jats:styled-content>\n 3 (\n OR<\/jats:styled-content>\n 0.577\n CI<\/jats:styled-content>\n 0.411 to 0.808);\n SDG<\/jats:styled-content>\n 8 (\n OR<\/jats:styled-content>\n 0.602\n CI<\/jats:styled-content>\n 0.440 to 0.823) and\n SDG<\/jats:styled-content>\n 16 (\n OR<\/jats:styled-content>\n 0.686\n CI<\/jats:styled-content>\n 0.505 to 0.933). Access to multiple\n SDG<\/jats:styled-content>\n \u2010aligned provisions showed a strongly graded reduction in potential mortality risk: Among adolescents living with\n HIV<\/jats:styled-content>\n , potential mortality risk was 38.5% with access to no\n SDG<\/jats:styled-content>\n \u2010aligned provisions, and 9.3% with access to all four.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n SDG<\/jats:styled-content>\n \u2010aligned provisions across a range of\n SDG<\/jats:styled-content>\n s were associated with reduced potential mortality risk among adolescents living with\n HIV<\/jats:styled-content>\n . Access to multiple provisions has the potential to substantially improve survival, suggesting the value of connecting and combining\n SDG<\/jats:styled-content>\n s in our response to paediatric and adolescent\n HIV<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jia2.25056","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T10:10:21Z","timestamp":1519726221000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Sustainable Survival for adolescents living with\n HIV<\/scp>\n : do\n SDG<\/scp>\n \u2010aligned provisions reduce potential mortality risk?"],"prefix":"10.1002","volume":"21","author":[{"given":"Lucie","family":"Cluver","sequence":"first","affiliation":[{"name":"Department of Social Policy and Intervention University of Oxford Oxford United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Pantelic","sequence":"additional","affiliation":[{"name":"Department of Social Policy and Intervention University of Oxford Oxford United Kingdom"},{"name":"International HIV\/AIDS Alliance Hove United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Orkin","sequence":"additional","affiliation":[{"name":"Department of Social Policy and Intervention University of Oxford Oxford United Kingdom"},{"name":"Development Pathways to Health Research Unit University of Witwatersrand Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elona","family":"Toska","sequence":"additional","affiliation":[{"name":"Department of Social Policy and Intervention University of Oxford Oxford United Kingdom"},{"name":"AIDS and Society Research Unit University of Cape Town Cape Town South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Medley","sequence":"additional","affiliation":[{"name":"Department of Social Policy and Intervention University of Oxford Oxford United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Sherr","sequence":"additional","affiliation":[{"name":"Department of Global Health University College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,27]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"United Nations.Transforming our world: The 2030 agenda for Sustainable Development. 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