{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:07:42Z","timestamp":1790222862079,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI094562"],"award-info":[{"award-number":["R01AI094562"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R34AI091446"],"award-info":[{"award-number":["R34AI091446"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Intern AIDS Soc"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Reducing high\u2010risk behaviours (i.e. multiple partnership, condomless anal\/vaginal sex, alcohol use before sex, illicit drug use) after <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> diagnosis is critical for curtailing <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> transmission. We designed an intervention to explore peer\u2010 counselling in reducing high\u2010risk behaviours among newly diagnosed <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive Chinese men who have sex with men (<jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We randomized 367 newly diagnosed <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive men to either standard\u2010of\u2010care (<jats:styled-content style=\"fixed-case\">SOC<\/jats:styled-content>; n\u00a0=\u00a0183) or peer\u2010counselling intervention (n\u00a0=\u00a0184), and followed them for 12\u00a0months (visit at 0\u2010, 3\u2010, 6\u2010, 9\u2010 and 12\u2010month). <jats:styled-content style=\"fixed-case\">SOC<\/jats:styled-content> participants received counselling on high\u2010risk behaviour reduction by clinic staff. Intervention participants received both <jats:styled-content style=\"fixed-case\">SOC<\/jats:styled-content> and peer counselling. A generalized estimating equation was used to compare pre\u2010post diagnosis high\u2010risk behaviour change; logistic regression was used to assess the likelihood of practicing high\u2010risk behaviours between intervention and <jats:styled-content style=\"fixed-case\">SOC<\/jats:styled-content> participants. Both intent\u2010to\u2010treat and per\u2010protocol (full\u2010dosage) approaches were used for the analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For pre\u2010 and post\u2010diagnosis comparisons, multiple partnership fell from 50% to 16% (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), alcohol use before sex from 23% to 9% (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.001), illicit drug use from 33% to 6% (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), condomless anal sex from 47% to 4% (insertive from 23% to 2%; receptive from 36% to 3%; <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). In the intent\u2010to\u2010treat analysis accounting for repeated measures, peer counselling was more likely to reduce insertive anal sex (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content>\u00a0=\u00a00.65; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.45 to 0.94), condomless anal sex (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content>\u00a0=\u00a00.27; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.10 to 0.64) and illicit drug use (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content>\u00a0=\u00a00.32; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.16 to 0.64). In the per\u2010protocol analysis, peer counselling was associated with a lower likelihood of using illicit drug (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a00.23; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.07 to 0.81) and having condomless vaginal sex with women (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a00.12; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.07 to 0.98).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We observed a 14 to 43% decrease in the prevalence of selected high\u2010risk behaviours after <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> diagnosis. Peer counselling had a greater impact in reducing condomless anal sex with men, illicit drug use and condomless vaginal sex with women over time. Future studies with exclusive peer\u2010counselling arm are necessary to test its efficacy and effectiveness among Chinese <jats:styled-content style=\"fixed-case\">MSM<\/jats:styled-content>.<\/jats:p><jats:p>Clinical Trial Number: NCT01904877<\/jats:p><\/jats:sec>","DOI":"10.1002\/jia2.25079","type":"journal-article","created":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T09:49:02Z","timestamp":1518428942000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Peer counselling versus standard\u2010of\u2010care on reducing high\u2010risk behaviours among newly diagnosed <scp>HIV<\/scp>\u2010positive men who have sex with men in Beijing, China: a randomized intervention study"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2515-4431","authenticated-orcid":false,"given":"Yu","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Public Health Sciences 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