{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:33:36Z","timestamp":1790062416873,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T00:00:00Z","timestamp":1586908800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Expertise France through the 5% Initiative program","award":["14SANIN204"],"award-info":[{"award-number":["14SANIN204"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Intern AIDS Soc"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Frequent HIV testing of at\u2010risk individuals is crucial to detect and treat infections early and prevent transmissions. We assessed the effect of reminders on HIV retesting uptake.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was conducted within a programme involving four facilities providing free\u2010of\u2010charge HIV, syphilis and hepatitis B and C testing and counselling in northern Thailand. Individuals found HIV negative and identified at risk by counsellors were invited to participate in a three\u2010arm, open\u2010label, randomized, controlled trial comparing: (a) \u201cNo Appointment &amp; No Reminder\u201d (control arm); (b) \u201cNo Appointment but Reminder\u201d: short message service (SMS) sent 24\u00a0weeks after the enrolment visit to remind booking an appointment, and sent again one week later if no appointment was booked; and (c) \u201cAppointment &amp; Reminder\u201d: appointment scheduled during the enrolment visit and SMS sent one week before appointment to ask for confirmation; if no response: single call made within one business day. The primary endpoint was a HIV retest within seven months after the enrolment visit. The cost of each reminder strategy was calculated as the sum of the following costs in United States dollars (USD): time spent by participants, counsellors and hotline staff; phone calls made; and SMS sent. The target sample size was 217 participants per arm (651 overall).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between April and November 2017, 651 participants were randomized. The proportion presenting for HIV retesting within seven months was 11.2% (24\/215) in the control arm, versus 19.3% (42\/218) in \u201cNo Appointment but Reminder\u201d (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.023) and 36.7% (80\/218) in \u201cAppointment &amp; Reminder\u201d (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). Differences in proportions compared to the control arm were respectively +8.1% (95% CI: +1.4% to +14.8%) and +25.5% (+17.9% to +33.2%). The incremental cost\u2010effectiveness ratios of \u201cNo Appointment but Reminder\u201d and \u201cAppointment &amp; Reminder\u201d compared to the control arm were respectively USD 0.05 and USD 0.14 per participant for each 5% increase in HIV retesting uptake within seven months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Scheduling an appointment and sending a reminder one week before was a simple, easy\u2010to\u2010implement and affordable intervention that significantly increased HIV retesting uptake in these at\u2010risk individuals. The personal phone call to clients probably contributed, and also improved service efficiency.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jia2.25478","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T16:12:21Z","timestamp":1586967141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Appointment reminders to increase uptake of HIV retesting by at\u2010risk individuals: a randomized controlled study in Thailand"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0820-5305","authenticated-orcid":false,"given":"Nicolas","family":"Salvadori","sequence":"first","affiliation":[{"name":"Institut de recherche pour le d\u00e9veloppement (IRD)\u2010PHPT Marseille France"},{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierrick","family":"Adam","sequence":"additional","affiliation":[{"name":"Institut de recherche pour le d\u00e9veloppement (IRD)\u2010PHPT Marseille France"},{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"},{"name":"Department of Epidemiology, Biostatistics and Occupational Health McGill University Montreal Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Yves","family":"Mary","sequence":"additional","affiliation":[{"name":"INSERM U1153 Team ECSTRA Universit\u00e9 Paris Diderot \u2010 Paris 7 H\u00f4pital Saint\u2010Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Decker","sequence":"additional","affiliation":[{"name":"Institut de recherche pour le d\u00e9veloppement (IRD)\u2010PHPT Marseille France"},{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Sabin","sequence":"additional","affiliation":[{"name":"Institut de recherche pour le d\u00e9veloppement (IRD)\u2010PHPT Marseille France"},{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Chevret","sequence":"additional","affiliation":[{"name":"INSERM U1153 Team ECSTRA Universit\u00e9 Paris Diderot \u2010 Paris 7 H\u00f4pital Saint\u2010Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surachet","family":"Arunothong","sequence":"additional","affiliation":[{"name":"Department of Disease Control Ministry of Public Health Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woottichai","family":"Khamduang","sequence":"additional","affiliation":[{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prapan","family":"Luangsook","sequence":"additional","affiliation":[{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Visitsak","family":"Suksa\u2010ardphasu","sequence":"additional","affiliation":[{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jullapong","family":"Achalapong","sequence":"additional","affiliation":[{"name":"Chiangrai Prachanukroh Hospital Chiang Rai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Rouzioux","sequence":"additional","affiliation":[{"name":"Laboratoire de Virologie \u2010 EA 3620 Universit\u00e9 Paris Descartes H\u00f4pital Necker Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wasna","family":"Sirirungsi","sequence":"additional","affiliation":[{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Ngo\u2010Giang\u2010Huong","sequence":"additional","affiliation":[{"name":"Institut de recherche pour le d\u00e9veloppement (IRD)\u2010PHPT Marseille France"},{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"},{"name":"Department of Immunology and Infectious Diseases Harvard T.H. Chan School of Public Health Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzague","family":"Jourdain","sequence":"additional","affiliation":[{"name":"Institut de recherche pour le d\u00e9veloppement (IRD)\u2010PHPT Marseille France"},{"name":"Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,15]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Joint United Nations Programme on HIV\/AIDS.Global AIDS update 2019 \u2010 Communities at the centre[Internet].Switzerland:UNAIDS; [cited 2019 Jul 31]. Available from:https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/2019\u2010global\u2010AIDS\u2010update_en.pdf"},{"key":"e_1_2_9_3_1","unstructured":"Joint United Nations Programme on HIV\/AIDS.UNAIDS Data 2019[Internet].Switzerland:UNAIDS; [cited 2019 Jul 31]. 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