{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:30:08Z","timestamp":1777573808291,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T00:00:00Z","timestamp":1617667200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1R01AI114310"],"award-info":[{"award-number":["1R01AI114310"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["NIAID K24AI143471"],"award-info":[{"award-number":["NIAID K24AI143471"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J. Intern. AIDS Soc."],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The COVID\u201019 pandemic is impacting HIV care globally, with gaps in HIV treatment expected to increase HIV transmission and HIV\u2010related mortality. We estimated how COVID\u201019\u2010related disruptions could impact HIV transmission and mortality among men who have sex with men (MSM) in four cities in China, over a one\u2010 and five\u2010year time horizon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Regional data from China indicated that the number of MSM undergoing facility\u2010based HIV testing reduced by 59% during the COVID\u201019 pandemic, alongside reductions in ART initiation (34%), numbers of all sexual partners (62%) and consistency of condom use (25%), but initial data indicated no change in viral suppression. A mathematical model of HIV transmission\/treatment among MSM was used to estimate the impact of disruptions on HIV infections\/HIV\u2010related deaths. Disruption scenarios were assessed for their individual and combined impact over one and five years for 3\/4\/6\u2010month disruption periods, starting from 1 January 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our model predicted new HIV infections and HIV\u2010related deaths would be increased most by disruptions to viral suppression, with 25% reductions (25% virally suppressed MSM stop taking ART) for a three\u2010month period increasing HIV infections by 5% to 14% over one year and deaths by 7% to 12%. Observed reductions in condom use increased HIV infections by 5% to 14% but had minimal impact (&lt;1%) on deaths. Smaller impacts on infections and deaths (&lt;3%) were seen for disruptions to facility HIV testing and ART initiation, but reduced partner numbers resulted in 11% to 23% fewer infections and 0.4% to 1.0% fewer deaths. Longer disruption periods (4\/6\u00a0months) amplified the impact of disruption scenarios. When realistic disruptions were modelled simultaneously, an overall decrease in new HIV infections occurred over one year (3% to 17%), but not for five years (1% increase to 4% decrease), whereas deaths mostly increased over one year (1% to 2%) and five years (1.2 increase to 0.3 decrease).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The overall impact of COVID\u201019 on new HIV infections and HIV\u2010related deaths is dependent on the nature, scale and length of the various disruptions. Resources should be directed to ensuring levels of viral suppression and condom use are maintained to mitigate any adverse effects of COVID\u201019\u2010related disruption on HIV transmission and control among MSM in China.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jia2.25697","type":"journal-article","created":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T03:21:20Z","timestamp":1617679280000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["The impact of disruptions due to COVID\u201019 on HIV transmission and control among men who have sex with men in China"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3013-4179","authenticated-orcid":false,"given":"Ross D","family":"Booton","sequence":"first","affiliation":[{"name":"University of Bristol Bristol United Kingdom"},{"name":"MRC Centre for Global Infectious Disease Analysis Imperial College London London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gengfeng","family":"Fu","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Center for Disease Control and Prevention Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"MacGregor","sequence":"additional","affiliation":[{"name":"University of Bristol Bristol United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjun","family":"Li","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Center for Disease Control and Prevention Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5784-7403","authenticated-orcid":false,"given":"Jason J","family":"Ong","sequence":"additional","affiliation":[{"name":"Social Entrepreneurship to Spur Health (SESH) Global Guangzhou China"},{"name":"Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London United Kingdom"},{"name":"Central Clinical School Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2804-1181","authenticated-orcid":false,"given":"Joseph D","family":"Tucker","sequence":"additional","affiliation":[{"name":"Social Entrepreneurship to Spur Health (SESH) Global Guangzhou China"},{"name":"Faculty of Infectious and Tropical Diseases London School of Hygiene &amp; Tropical Medicine London United Kingdom"},{"name":"University of North Carolina Project\u2010China Guangzhou China"},{"name":"University of North Carolina at Chapel Hill Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine ME","family":"Turner","sequence":"additional","affiliation":[{"name":"University of Bristol Bristol United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiming","family":"Tang","sequence":"additional","affiliation":[{"name":"Social Entrepreneurship to Spur Health (SESH) Global Guangzhou China"},{"name":"University of North Carolina Project\u2010China Guangzhou China"},{"name":"University of North Carolina at Chapel Hill Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8291-5890","authenticated-orcid":false,"given":"Peter","family":"Vickerman","sequence":"additional","affiliation":[{"name":"University of Bristol Bristol United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7050-4787","authenticated-orcid":false,"given":"Kate M","family":"Mitchell","sequence":"additional","affiliation":[{"name":"MRC Centre for Global Infectious Disease Analysis Imperial College London London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,6]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Joint United Nations Programme on HIV\/AIDS (UNAIDS).World AIDS day 2019 fact sheet. Glob HIV AIDS Stat.2019."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60821-6"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4559-1"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0201953"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02903-4"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30105-3"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02905-2"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02894-2"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30138-7"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02935-w"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02969-0"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02871-9"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-02893-3"},{"issue":"5","key":"e_1_2_10_15_1","first-page":"662","article-title":"Quick community survey on the impact of COVID\u201019 outbreak for the healthcare of people living with HIV","volume":"41","author":"Guo W","year":"2020","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"e_1_2_10_16_1","unstructured":"World Health Organization.Disruption in HIV Hepatitis and STI services due to COVID\u201019[Internet]. Global HIV Hepatitis and STI Programmes.2020[cited 2021 Feb 5]. Available from:https:\/\/www.who.int\/docs\/default\u2010source\/hiv\u2010hq\/disruption\u2010hiv\u2010hepatitis\u2010sti\u2010services\u2010due\u2010to\u2010covid19.pdf?sfvrsn=5f78b742_8"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30211-3"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(20)30288-6"},{"key":"e_1_2_10_19_1","unstructured":"UNAIDS.Topics: Key populations[Internet]. [cited 2020 Sep 28]. Available from:https:\/\/www.unaids.org\/en\/topic\/key\u2010populations"},{"key":"e_1_2_10_20_1","article-title":"Impact of the COVID\u201019 pandemic on HIV care continuum in Jiangsu, China","author":"Shi L\u2010E","year":"2020","journal-title":"SSRN Electronic Journal"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.13063"},{"key":"e_1_2_10_22_1","unstructured":"FuG.The current status of HIVST services in Jiangsu China. 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Guangzhou China;2020."},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002645"}],"container-title":["Journal of the International AIDS Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jia2.25697","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jia2.25697","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jia2.25697","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T16:26:15Z","timestamp":1693585575000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jia2.25697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1002\/jia2.25697"],"URL":"https:\/\/doi.org\/10.1002\/jia2.25697","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.10.08.20209072","asserted-by":"object"}]},"ISSN":["1758-2652","1758-2652"],"issn-type":[{"value":"1758-2652","type":"print"},{"value":"1758-2652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"2020-10-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e25697"}}