{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:32:30Z","timestamp":1791952350590,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Int AIDS Soc."],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Transgender women are at increased risk of acquiring HIV. Earlier studies reported lower retention in HIV care, antiretroviral therapy uptake, adherence and viral suppression. We assessed the stages of the HIV care continuum of transgender women in the Netherlands over an 11\u2010year period. In addition, we assessed new HIV diagnoses and late presentation, as well as disengagement from care, between 2011 and 2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using data from the Dutch national ATHENA cohort, we separately assessed viral suppression, as well as time to achieving viral suppression, among transgender women for each year between 2011 and 2021. We also assessed trends in new HIV diagnoses and late presentation (CD4 count of &lt;350 cells\/\u00b5l and\/or AIDS at diagnosis), and disengagement from care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Between 2011 and 2021, a total of 260 transgender women attended at least one HIV clinical visit. Across all years, &lt;90% of transgender women were virally suppressed (207\/239 [87%] in 2021). The number of new HIV diagnoses fluctuated for transgender women (\n                      <jats:italic>p<\/jats:italic>\n                      <jats:sub>trend<\/jats:sub>\n                      = 0.053) and late presentation was common (ranging between 10% and 67% of new HIV diagnoses). Of the 260 transgender women, 26 (10%) disengaged from care between 2011 and 2021 (incidence rate = 1.10 per 100 person\u2010years, 95% confidence interval = 0.75\u22121.61).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Between 2011 and 2021, less than 90% of transgender women linked to HIV care were virally suppressed. Late presentation at the time of diagnosis and disengagement from care were common. Efforts are needed to identify barriers to early HIV diagnosis and to optimize the different steps across the care continuum for transgender women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jia2.26317","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:54:54Z","timestamp":1723164894000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Assessing the HIV care continuum among transgender women during 11 years of follow\u2010up: results from the Netherlands\u2019 ATHENA observational cohort"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9538-1501","authenticated-orcid":false,"given":"Vita W.","family":"Jongen","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"},{"name":"Stichting hiv monitoring  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceranza","family":"Daans","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ard","family":"van Sighem","sequence":"additional","affiliation":[{"name":"Stichting hiv monitoring  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"Schim van der Loeff","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"},{"name":"Amsterdam UMC University of Amsterdam, Internal Medicine  Amsterdam The Netherlands"},{"name":"Amsterdam Institute for Infection and Immunity (AII)  Amsterdam The Netherlands"},{"name":"Amsterdam Public Health Research Institute (APH)  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kris","family":"Hage","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"},{"name":"Amsterdam Institute for Infection and Immunity (AII)  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camiel","family":"Welling","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"von Vaupel\u2010Klein","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"},{"name":"Trans United Europe  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"den Heijer","sequence":"additional","affiliation":[{"name":"Amsterdam UMC Vrije Universiteit Amsterdam, Internal Medicine  Amsterdam The Netherlands"},{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC VU University Medical Center  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar J. G.","family":"Peters","sequence":"additional","affiliation":[{"name":"Amsterdam Institute for Infection and Immunity (AII)  Amsterdam The Netherlands"},{"name":"Amsterdam UMC Vrije Universiteit Amsterdam, Internal Medicine  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"van der Valk","sequence":"additional","affiliation":[{"name":"Stichting hiv monitoring  Amsterdam The Netherlands"},{"name":"Amsterdam UMC University of Amsterdam, Internal Medicine  Amsterdam The Netherlands"},{"name":"Amsterdam Institute for Infection and Immunity (AII)  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Reiss","sequence":"additional","affiliation":[{"name":"Stichting hiv monitoring  Amsterdam The Netherlands"},{"name":"Amsterdam UMC University of Amsterdam, Internal Medicine  Amsterdam The Netherlands"},{"name":"Amsterdam Public Health Research Institute (APH)  Amsterdam The Netherlands"},{"name":"Amsterdam UMC University of Amsterdam, Global Health  Amsterdam The Netherlands"},{"name":"Amsterdam Institute for Global Health and Development  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Prins","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"},{"name":"Amsterdam UMC University of Amsterdam, Internal Medicine  Amsterdam The Netherlands"},{"name":"Amsterdam Institute for Infection and Immunity (AII)  Amsterdam The Netherlands"},{"name":"Amsterdam Public Health Research Institute (APH)  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0512-2109","authenticated-orcid":false,"given":"Elske","family":"Hoornenborg","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Public Health Service Amsterdam  Amsterdam The Netherlands"},{"name":"Amsterdam UMC University of Amsterdam, Internal Medicine  Amsterdam The Netherlands"},{"name":"Amsterdam Institute for Infection and Immunity (AII)  Amsterdam The Netherlands"},{"name":"Amsterdam Public Health Research Institute (APH)  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the ATHENA observational HIV cohort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,8]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0260063"},{"key":"e_1_2_12_3_1","unstructured":"UNAIDS.UNAIDS data 2021. 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