{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:18:28Z","timestamp":1755217108219,"version":"3.43.0"},"reference-count":33,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:00:00Z","timestamp":1750896000000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Int AIDS Soc."],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>In Eswatini, HIV incidence among adolescent girls and young women (AGYW), aged 15\u201324 years, is 10 times that of their male peers. Despite the World Health Organization's 2014 recommendation for post\u2010exposure prophylaxis (PEP) to be available for all HIV exposures, it has been underutilized among youth. PEP is an effective prevention method, and a better understanding of the characteristics, risk factors and behaviours that are associated with PEP awareness, as a precursor to effective use, is needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using data from the 2022 Eswatini Violence Against Children and Youth Survey, we used logistic regression models to explore the relationships between PEP awareness and a set of hypothesized explanatory variables among AGYW aged 13\u201324 years who had ever had sex (<jats:italic>N<\/jats:italic> = 2648). Explanatory variables included socio\u2010demographic characteristics, sexual risk factors and sexual health behaviours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A slight majority (57.3%) of AGYW who had ever had sex were aware of PEP as an HIV prevention method. PEP awareness increased with age (aOR 1.1, 95% CI 1.0, 1.1) and was higher among AGYW who had a sexual partner whose age was 5 or more years older in the past 12 months (aOR 1.4, 95% CI 1.1, 1.9), those who had ever taken part in an HIV prevention programme (aOR 1.6, 95% CI 1.2, 2.3) and those who had ever heard of pre\u2010exposure prophylaxis (aOR 8.1, 95% CI 6.4, 10.2). Participants who were ever married or partnered (aOR 0.7, 95% CI 0.5, 1.0) and those who engaged in inconsistent condom use with non\u2010spouse\/main partner or multiple partners in the past 12 months (aOR 0.8, 95% CI 0.6, 1.00) had lower odds of knowing about PEP in the adjusted model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We identified sub\u2010optimal PEP awareness among Swazi AGYW who had ever had sex. Our findings suggest that engagement in HIV prevention programmes increased PEP awareness and that knowing about pre\u2010exposure prophylaxis (PrEP) was associated with PEP awareness. Future efforts could include tailored PEP awareness activities and campaigns to resonate with AGYW at elevated risk of HIV and integration of PEP education into routine sexual and reproductive service delivery and school\u2010based HIV curriculum.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jia2.26486","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T13:05:05Z","timestamp":1750943105000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors associated with PEP awareness among adolescent girls and young women in Eswatini"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7277-3350","authenticated-orcid":false,"given":"Anne","family":"Laterra","sequence":"first","affiliation":[{"name":"Division of Global HIV and Tuberculosis U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie Spaid","family":"Miedema","sequence":"additional","affiliation":[{"name":"Division of Violence Prevention U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Global HIV and Tuberculosis U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phumzile","family":"Mndzebele","sequence":"additional","affiliation":[{"name":"Division of Global HIV and Tuberculosis U.S. Centers for Disease Control and Prevention  Mbabane Eswatini"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nozipho","family":"Nzuza\u2010Motsa","sequence":"additional","affiliation":[{"name":"Eswatini Ministry of Health  Mbabane Eswatini"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana Nasir","family":"Charania","sequence":"additional","affiliation":[{"name":"Division of Violence Prevention U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Ong","sequence":"additional","affiliation":[{"name":"Division of Global HIV and Tuberculosis U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meagan","family":"Cain","sequence":"additional","affiliation":[{"name":"Division of Global HIV and Tuberculosis U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udhayashankar","family":"Kanagasabai","sequence":"additional","affiliation":[{"name":"Division of Global HIV and Tuberculosis U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thobile","family":"Mkhonta","sequence":"additional","affiliation":[{"name":"U.S. Agency for International Development  Mbabane Eswatini"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Chiang","sequence":"additional","affiliation":[{"name":"Division of Violence Prevention U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis Boateng","family":"Annor","sequence":"additional","affiliation":[{"name":"Division of Violence Prevention U.S. Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle R.","family":"Adler","sequence":"additional","affiliation":[{"name":"Eswatini Ministry of Health  Mbabane Eswatini"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,26]]},"reference":[{"volume-title":"Describing the \u2018end of AIDS as a public health threat\u2019","year":"2023","author":"UNAIDS","key":"e_1_2_12_2_1"},{"doi-asserted-by":"publisher","key":"e_1_2_12_3_1","DOI":"10.18356\/9789210028370"},{"volume-title":"Ending inequalities and getting on track to end AIDS by 2030 \u2014 A summary of the commitments and targets within the United Nations General Assembly's 2021 Political Declaration on HIV and AIDS","year":"2022","author":"UNAIDS","key":"e_1_2_12_4_1"},{"volume-title":"Swaziland HIV Incidence Measurement Survey 2 (SHIMS2) 2016\u20132017. 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