{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:33:38Z","timestamp":1791203618002,"version":"4.2.0"},"reference-count":43,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100004423","name":"World Health Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010877","name":"ViiV Healthcare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008810","name":"NSW Ministry of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008810","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Int AIDS Soc."],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Scaling up pre\u2010exposure prophylaxis (PrEP) for HIV among men who have sex with men (MSM) and transgender women (TGW) in the Asia\u2010Pacific region has been slow. We identified the drivers of PrEP use and forecasted PrEP uptake given different PrEP programmes for MSM and TGW living in 15 countries and territories in Asia and Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Separate online discrete choice experiment surveys for MSM and TGW were distributed in 15 Asian countries and territories and Australia between May and November 2022. We used random parameters logit models to estimate the relative importance of service attributes and predicted PrEP uptake for different programme configurations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 21,943 participants included in the MSM survey and 1522 in the TGW survey, the mean age was 31.7 (\u00b19.5) years and 28.1 (\u00b17.0) years, respectively. Cost emerged as the primary driver of PrEP use for MSM and TGW across countries, followed by the type of PrEP. When switching from the least preferred PrEP programme (i.e. very high service fee, PrEP implant, rare kidney problems as side effects of PrEP and a 2\u2010monthly clinic visit) to an optimal programme (i.e. free access to PrEP via peer\u2010led community clinics which offered sexually transmitted infection [STI] testing, and a 6\u201312 monthly visit), the predicted PrEP uptake could improve by over 50% for MSM in Australia, China, Hong Kong SAR China, Japan, the Philippines, Taiwan (China) and Thailand, and 37% for TGW. Compared to those at lower risk of HIV, free access was more preferred by MSM at a higher risk of HIV, while telehealth was more preferred by TGW at a substantial risk of HIV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Tailoring services to local contexts, including ensuring affordability, preferred type of PrEP and providing differentiated services, could accelerate the uptake of PrEP among MSM and TGW in Asia and Australia. Novel innovations, such as STI and HIV self\u2010testing, should be explored as alternatives to conventional testing, given that most MSM and TGW prefer less frequent clinic visits and long\u2010acting PrEP options.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jia2.70025","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T05:34:56Z","timestamp":1755754496000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Preferences for HIV pre\u2010exposure prophylaxis among men who have sex with men and trans women in 15 countries and territories in Asia and Australia: a discrete choice experiment"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9712-9262","authenticated-orcid":false,"given":"Warittha","family":"Tieosapjaroen","sequence":"first","affiliation":[{"name":"The School of Translational Medicine Monash University  Melbourne Victoria Australia"},{"name":"Melbourne Sexual Health Centre, Alfred Health  Carlton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5834-8278","authenticated-orcid":false,"given":"Benjamin R.","family":"Bavinton","sequence":"additional","affiliation":[{"name":"Kirby Institute, University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2629-6407","authenticated-orcid":false,"given":"Heather\u2010Marie A.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"UNAIDS Regional Office for Asia and the Pacific  Bangkok Thailand"},{"name":"Global HIV, Hepatitis and STIs Programme, World Health Organization  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9581-1011","authenticated-orcid":false,"given":"Curtis","family":"Chan","sequence":"additional","affiliation":[{"name":"Kirby Institute, University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim E.","family":"Green","sequence":"additional","affiliation":[{"name":"The Program for Appropriate Technology in Health  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0036-3165","authenticated-orcid":false,"given":"Nittaya","family":"Phanuphak","sequence":"additional","affiliation":[{"name":"Institute of HIV Research and Innovation  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Midnight","family":"Poonkasetwattana","sequence":"additional","affiliation":[{"name":"Asia Pacific Coalition on Male Sexual Health  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicky S.","family":"Suwandi","sequence":"additional","affiliation":[{"name":"Asian Pacific Transgender Network  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doug","family":"Fraser","sequence":"additional","affiliation":[{"name":"Kirby Institute, University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Boonyapisomparn","sequence":"additional","affiliation":[{"name":"Asian Pacific Transgender Network  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Cassell","sequence":"additional","affiliation":[{"name":"Family Health International 360  Hanoi Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[{"name":"The School of Translational Medicine Monash University  Melbourne Victoria Australia"},{"name":"Melbourne Sexual Health Centre, Alfred Health  Carlton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9026-707X","authenticated-orcid":false,"given":"Weiming","family":"Tang","sequence":"additional","affiliation":[{"name":"The University of North Carolina at Chapel Hill Project\u2010China  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason J.","family":"Ong","sequence":"additional","affiliation":[{"name":"The School of Translational Medicine Monash University  Melbourne Victoria Australia"},{"name":"Melbourne Sexual Health Centre, Alfred Health  Carlton Victoria Australia"},{"name":"Faculty of Infectious and Tropical Diseases London School of Hygiene and Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Joint United Nations Programme on HIV\/AIDS. 2025 AIDS targets. 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