{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T23:15:42Z","timestamp":1789168542976,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Int AIDS Soc."],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The elimination of vertical transmission of HIV is a global health priority endorsed by the Pan American Health Organization (PAHO) and the World Health Organization (WHO), aligned with the Sustainable Development Goals (SDGs). Brazil has made substantial progress towards this goal through sustained investment in universal health policies and a rights\u2010based approach to healthcare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Brazil's national HIV response is anchored in the Unified Health System (Sistema \u00danico de Sa\u00fade\u2014SUS), a universal, decentralized and participatory health system that ensures access to prevention, diagnosis, treatment and monitoring. Tripartite governance\u2014across federal, state and municipal levels\u2014combined with strong community engagement, has enabled coordinated policy implementation at scale. This framework has supported high coverage of antenatal care (&gt;98%), HIV testing (&gt;95%) and antiretroviral therapy among pregnant women living with HIV (&gt;95%) in recent years. Vertical transmission rates of HIV declined from 3.73% in 2015 to 1.78% in 2023, remaining below the elimination threshold. The annual rate of new paediatric HIV acquisitions also declined to low levels, being 5.99 per 100,000 live births in 2023, far below the PAHO\/WHO targets. A certification for states and municipalities strategy further accelerated progress toward the elimination by strengthening accountability, improving data quality and engaging local health systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Brazil's experience demonstrates that HIV vertical transmission elimination is feasible in large and unequal settings when supported by strong governance, integrated health systems and sustained political commitment. The certification of vertical transmission elimination of HIV by PAHO\/WHO in 2025 represents a major milestone and offers valuable lessons for global health. Brazil remains committed to sustaining stainability of this certification and to advancing efforts for the elimination of other vertically transmitted infections, including syphilis, hepatitis B, Human T\u2010cell lymphotropic virus (HTLV) and Chagas disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jia2.70123","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:22:22Z","timestamp":1781875342000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["From Policy to Practice: Brazil's Pathway to Eliminating Vertical Transmission of HIV as a Public Health Milestone"],"prefix":"10.1002","volume":"29","author":[{"given":"P\u00e2mela Cristina","family":"Gaspar","sequence":"first","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lica Espinosa","family":"Miranda","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Infectious Diseases Health Sciences Center Federal University of Esp\u00edrito Santo  Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9520-8538","authenticated-orcid":false,"given":"Leonor Henriette de","family":"Lannoy","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Roberta Pati","family":"Pascon","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for 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Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula Betaressi","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alisson","family":"Bigolin","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane Tiago Bernardo de","family":"Matos","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia Rejane","family":"Colombo","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Gon\u00e7alves","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Gasperin","family":"Martinazzo","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adele Schwartz","family":"Benzaken","sequence":"additional","affiliation":[{"name":"Heitor Vieira Dourado Tropical Medicine Foundation, State University of Amazonas (UEA) Manaus Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Draurio","family":"Barreira","sequence":"additional","affiliation":[{"name":"Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari\u00e2ngela Batista Galv\u00e3o","family":"Sim\u00e3o","sequence":"additional","affiliation":[{"name":"Secretariat for Health and Environmental Surveillance Ministry of Health of Brazil  Bras\u00edlia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Brazilian Elimination Vertical Transmission Group (Brazilian EVT Group)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"EMTCT Plus. 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