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Mpox vaccination efforts in Brazil have been limited by delayed procurement, restricted eligibility criteria and structural access barriers. Understanding vaccination use, correlates of uptake and characteristics of individuals previously diagnosed with mpox is essential to guide equitable prevention strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted an online cross\u2010sectional survey between August and December 2024 among individuals recruited through social media and dating apps. Eligible participants were aged \u226518 years, identified as a sexual and gender diverse person, and residing in Brazil. Primary outcomes were previous mpox vaccination and mpox diagnosis. Sociodemographic, behavioural, internalized LGBTQIAPN+phobia and HIV\/sexually transmitted infections (STIs) variables were collected. Adjusted logistic regression models identified independent factors associated with both outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 9546 respondents, most were cisgender men (91.8%), aged &gt;30 years (81.5%) and residing in capital cities (77.2%). Overall, mpox vaccination coverage was 4.9%; nearly half received only one dose, and one quarter were vaccinated outside Brazil. Previous mpox diagnosis was reported by 2.1% of respondents, with 76.5% seeking healthcare and 7.0% requiring hospitalization. Factors associated with previous mpox vaccination were self\u2010identification as White (aOR = 1.36; 95% CI: 1.10\u22121.69), more than five sex partners (aOR = 1.29; 95% CI: 1.03\u20131.62), living with HIV (aOR = 3.40; 95% CI: 2.59\u20134.47), current\/prior HIV pre\u2010exposure prophylaxis (PrEP) use (aOR = 1.88; 95% CI: 1.41\u20132.53) and internalized LGBTQIAPN+phobia score (aOR = 0.80; 95% CI: 0.71\u22120.90). Factors associated with previous mpox diagnosis were living in capital cities (aOR = 1.88; 95% CI: 1.17\u20133.20), more than five sex partners (aOR = 1.93; 95% CI: 1.35\u22122.79), stimulant drug use (aOR = 1.61; 95% CI: 1.14\u20132.25), any STI diagnosis (aOR = 2.41; 95% CI: 1.74\u20133.33), living with HIV (aOR = 3.73; 95% CI: 2.31\u20136.25) and current\/prior PrEP use (aOR = 2.35; 95% CI: 1.43\u22124.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Mpox vaccination among sexual and gender diverse populations in Brazil remains critically low. Findings highlight structural barriers, including vaccine scarcity, delayed rollout and stigma, that hinder equitable vaccine access. Integrating mpox vaccination into combined HIV\/STI prevention services, adopting differentiated care delivery models and partnering with community\u2010led organizations are essential to expanding reach, improving dose completion and reducing health inequities during ongoing and future outbreaks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jia2.70143","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:16:04Z","timestamp":1784956564000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mpox Vaccination and Diagnosis Among Sexual and Gender Diverse Populations in Brazil: Results From a Large Nationwide Online Survey"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0195-0337","authenticated-orcid":false,"given":"Mayara Secco Torres","family":"Silva","sequence":"first","affiliation":[{"name":"Instituto Nacional de Infectologia 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Moreira","family":"Jalil","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Infectologia Evandro Chagas Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Pimenta","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Infectologia Evandro Chagas Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"Benedetti","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Infectologia Evandro Chagas Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Wagner","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Infectologia Evandro Chagas Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valdilea 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Minist\u00e9rio da Sa\u00fade;2026[citado 15 de maio de 2026]. 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