{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T20:16:35Z","timestamp":1696796195977},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[1998,10,1]],"date-time":"1998-10-01T00:00:00Z","timestamp":907200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Malignant histiocytosis sarcoma virus (MHSV) arose as a recombinant of c-Harvey-ras murine sarcoma virus (Ha-MuSV) and Friend mink cell focus-forming virus (F-MCFV). It is a defective acute transforming retrovirus that, along with Friend murine leukemia helper virus (F-MuLV), induces malignant histiocytosis (MH) in susceptible adult mice. We have assessed the in vivo susceptibility to MHSV in inbred homozygous, F1 hybrid, congenic, and recombinant inbred (RI) mice. We have shown that: (1) in vivo resistance to MHSV is multigenic, regulated by MHC and non-MHC genes in a different fashion than with F-MCFV, F-MuLV, or Ha-MuSV; (2) using BXD RI mice, the resistance phenotype is linked with 95.8% probability to two linked loci, Pmv-9 and Iapls3-14, on chromosome 13 (homologous to the area of human chromosome 5 for which a chromosomal break point at position 5q35 is associated with human MH); and (3) CD4+ T cells are critical for MHSV resistance. J. Leukoc. Biol. 64: 441\u2013450; 1998.<\/jats:p>","DOI":"10.1002\/jlb.64.4.441","type":"journal-article","created":{"date-parts":[[2018,1,12]],"date-time":"2018-01-12T18:58:59Z","timestamp":1515783539000},"page":"441-450","source":"Crossref","is-referenced-by-count":4,"title":["Genetic and immunological parameters governing <i>in vivo<\/i> susceptibility\/resistance to retrovirally induced murine malignant histiocytosis"],"prefix":"10.1093","volume":"64","author":[{"given":"Angela","family":"Panoskaltsis-Mortari","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplant Program , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Maarten","family":"Egeler","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplant Program , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas M","family":"Yaeger","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplant Program , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumiko","family":"Yoneji","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplant Program , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Schmitz","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Division of Special Hematology, University of Minnesota Hospital and Clinic , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Lilly","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, Albert Einstein College of Medicine , Bronx, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark E","family":"Nesbit","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplant Program , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce R","family":"Blazar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplant Program , Minneapolis, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1998,10,1]]},"container-title":["Journal of Leukocyte Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjlb.64.4.441","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jleukbio\/article-pdf\/64\/4\/441\/49736929\/jlb0441.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jleukbio\/article-pdf\/64\/4\/441\/49736929\/jlb0441.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T04:40:33Z","timestamp":1680669633000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jleukbio\/article\/64\/4\/441\/6976840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,10,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1998,10,1]]},"published-print":{"date-parts":[[1998,10,1]]}},"URL":"https:\/\/doi.org\/10.1002\/jlb.64.4.441","relation":{},"ISSN":["0741-5400","1938-3673"],"issn-type":[{"value":"0741-5400","type":"print"},{"value":"1938-3673","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1998,10]]},"published":{"date-parts":[[1998,10,1]]}}}