{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:37:35Z","timestamp":1760661455205,"version":"build-2065373602"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,16]],"date-time":"2017-04-16T00:00:00Z","timestamp":1492300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DE 021055"],"award-info":[{"award-number":["DE 021055"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Labelled Comp Radiopharmac"],"published-print":{"date-parts":[[2017,5,30]]},"abstract":"<jats:p>Bacterial serine dipeptide lipids are known to promote inflammatory processes and are detected in human tissues associated with periodontal disease or atherosclerosis. Accurate quantification of bacterial serine lipid, specifically lipid 654 [((<jats:italic>S<\/jats:italic>)\u201015\u2010methyl\u20103\u2010((13\u2010methyltetradecanoyl)oxy)hexadecanoyl)glycyl\u2010<jats:sc>l<\/jats:sc>\u2010serine, (3<jats:italic>S<\/jats:italic>)\u2010<jats:sc>l<\/jats:sc>\u2010serine] isolated from <jats:italic>Porphyromonas gingivalis<\/jats:italic>, in biological samples requires the preparation of a stable isotope internal standard for sample supplementation and subsequent mass spectrometric analysis. This report describes the convergent synthesis of a deuterium\u2010substituted serine dipeptide lipid, which is an isotopically labeled homologue that represents a dominant form of serine dipeptide lipid recovered in bacteria.<\/jats:p>","DOI":"10.1002\/jlcr.3498","type":"journal-article","created":{"date-parts":[[2017,3,8]],"date-time":"2017-03-08T03:06:50Z","timestamp":1488942410000},"page":"274-285","source":"Crossref","is-referenced-by-count":8,"title":["Convergent synthesis of a deuterium\u2010labeled serine dipeptide lipid for analysis of biological samples"],"prefix":"10.1002","volume":"60","author":[{"given":"Christopher","family":"Dietz","sequence":"first","affiliation":[{"name":"Department of Chemistry The University of Connecticut  Storrs CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert B.","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Immunology The University of Connecticut Health Center  Farmington CT 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