{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:42:20Z","timestamp":1789000940206,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Labelled Comp Radiopharmac"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>We, herein, report the synthesis of <jats:sup>13<\/jats:sup>C<jats:sub>2<\/jats:sub>\u2010labeled natural products from the mugineic acid and avenic acid family. These phytosiderophores (\u201cplant iron carriers\u201d) are built up from non\u2010proteinogenic amino acids and play a key role in micronutrient uptake in gramineous plants. In this work, two central building blocks are prepared from labeled starting materials (<jats:sup>13<\/jats:sup>C<jats:sub>2<\/jats:sub>\u2010bromoacetic acid, <jats:sup>13<\/jats:sup>C<jats:sub>2<\/jats:sub>\u2010glycine) and further employed in our recently reported divergent, branched synthetic strategy delivering eight isotopically labeled phytosiderophores. The required labeled building blocks (<jats:sup>13<\/jats:sup>C<jats:sub>2<\/jats:sub>\u2010<jats:sc>l<\/jats:sc>\u2010allylglycine and a related hydroxylated derivative) were prepared via enantioselective phase\u2010transfer catalysis and enantio\u2010 and diastereoselective aldol condensation with a chiral auxiliary, respectively, both potentially valuable themselves for other synthetic routes toward labeled (natural) products.<\/jats:p>","DOI":"10.1002\/jlcr.4064","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T09:41:21Z","timestamp":1695721281000},"page":"428-434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Total synthesis of [<sup>13<\/sup>C<sub>2<\/sub>]\u2010labeled phytosiderophores of the mugineic and avenic acid families"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3080-7214","authenticated-orcid":false,"given":"Nicolas","family":"Kratena","sequence":"first","affiliation":[{"name":"Institute of Applied Synthetic Chemistry, TU Wien  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2835-1692","authenticated-orcid":false,"given":"Markus","family":"Draskovits","sequence":"additional","affiliation":[{"name":"Institute of Applied Synthetic Chemistry, TU Wien  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7709-1156","authenticated-orcid":false,"given":"Nina","family":"Biedermann","sequence":"additional","affiliation":[{"name":"Institute of Applied Synthetic Chemistry, TU Wien  Vienna 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