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In this study, we aimed to characterize the distribution of different types of salmon louse (<jats:italic>Lepeophtheirus salmonis<\/jats:italic>) exocrine glands and their site of secretion. The developmental appearance of each gland type was mapped and genes specifically expressed by glands were identified. Three types of tegumental (teg 1\u20133) glands and one labial gland type were found. The first glands to appear during development were teg 1 and teg 2 glands. They have ducts extending both dorsally and ventrally suggested to be important in lubricating the integument. Teg 1 glands were found to express two astacin metallopeptidases and a gene with fibronectin II domains, while teg 2 glands express a heme peroxidase. The labial glands were first identified in planktonic copepodids, with reservoirs that allows for storage of glandular products. The last gland type to appear during development was named teg 3 and was not seen before the preadult I stage when the lice become more virulent. Teg 3 glands have ducts ending ventrally at the host\u2010parasite contact area, and may secrete substances important for the salmon lice virulence. Salmon lice teg 3 and labial glands are thus likely to be especially important in the host\u2010parasite interaction. Proteins secreted from the salmon louse glands to its salmonid host skin or blood represents a potential interface where the host immune system can meet and elicit effective responses to sea lice antigens. The present study thus represents a fundamental basis for further functional studies and identification of possible vaccine candidates. J. Morphol. 277:1616\u20131630, 2016. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jmor.20611","type":"journal-article","created":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T03:52:47Z","timestamp":1474343567000},"page":"1616-1630","source":"Crossref","is-referenced-by-count":39,"title":["Exocrine glands of <scp><i>L<\/i><\/scp><i>epeophtheirus salmonis<\/i> (<scp>C<\/scp>opepoda: <scp>C<\/scp>aligidae): Distribution, developmental appearance, and site of secretion"],"prefix":"10.1002","volume":"277","author":[{"given":"Aina\u2010Cathrine","family":"\u00d8verg\u00e5rd","sequence":"first","affiliation":[{"name":"Disease and Pathogen Transmission SLCR\u2010Sea Lice Research Centre, Institute of Marine Research Nordnesgaten 50, Pb. 1870 Nordnes Bergen NO\u20105817 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars A.","family":"Hamre","sequence":"additional","affiliation":[{"name":"Department of Biology SLCR\u2010Sea Lice Research Centre, University of Bergen Thorm\u00f8hlensgt. 55, Pb. 7803 Bergen NO\u20105020 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Harasimczuk","sequence":"additional","affiliation":[{"name":"Disease and Pathogen Transmission SLCR\u2010Sea Lice Research Centre, Institute of Marine Research Nordnesgaten 50, Pb. 1870 Nordnes Bergen NO\u20105817 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sussie","family":"Dalvin","sequence":"additional","affiliation":[{"name":"Disease and Pathogen Transmission SLCR\u2010Sea Lice Research Centre, Institute of Marine Research Nordnesgaten 50, Pb. 1870 Nordnes Bergen NO\u20105817 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Nilsen","sequence":"additional","affiliation":[{"name":"Department of Biology SLCR\u2010Sea Lice Research Centre, University of Bergen Thorm\u00f8hlensgt. 55, Pb. 7803 Bergen NO\u20105020 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sindre","family":"Grotmol","sequence":"additional","affiliation":[{"name":"Department of Biology SLCR\u2010Sea Lice Research Centre, University of Bergen Thorm\u00f8hlensgt. 55, Pb. 7803 Bergen NO\u20105020 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2014.12.006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1051970103"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1051970207"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0025315400032665"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0025315400030939"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2980403"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1139\/z01-104"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2013.01.006"},{"key":"e_1_2_6_10_1","unstructured":"BellS.2001. 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