{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:11:49Z","timestamp":1772118709586,"version":"3.50.1"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:00:00Z","timestamp":1740182400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Morphology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In mammals the fila olfactoria, fascicles of axons coursing from sensory neurons in the olfactory epithelium to the glomeruli of the olfactory bulb, not only have a topographic projection pattern but also serve as routes for cerebrospinal fluid (CSF) drainage from around the brain. Les is known about the fila olfactoria in nonmammalian taxa. This work explores the fila olfactoria of the American alligator (\n                    <jats:italic>Alligator mississippiensis<\/jats:italic>\n                    ) using a combination of gross dissection, histology, Diffusible Iodine\u2010based contrast\u2010enhanced computed tomography, latex corrosion casting, and India ink tracers. In Crocodylians, as in other nonmammalian vertebrates, the fila olfactoria courses through a foramen in the nasal capsule rather than an ethmoidal cribriform plate. In\n                    <jats:italic>Alligator<\/jats:italic>\n                    this foramen is filled by dense connective tissue; prominent perineural spaces extend through the connective tissue, effectively making it perforate like the cribriform plate. Latex or India ink introduced into the cranial CSF pass through the dense connective to reach the submucosa of the olfactory epithelium, suggesting that Crocodylians have the same cranial CSF drainage pattern as mammals. In\n                    <jats:italic>Alligator<\/jats:italic>\n                    , the fila olfactoria is asymmetric, with more fascicles entering the ventral and lateral surfaces of the olfactory bulb than the dorsal or medial surfaces. If individual fascicles of the fila olfactoria are traced in\n                    <jats:italic>Alligator<\/jats:italic>\n                    , a clear topographic projection emerges; with medial and lateral polarity maintained between olfactory epithelium and olfactory bulb, and a rostral\u2010caudal polarity projecting as dorsal\u2010ventral on the olfactory bulb.\n                  <\/jats:p>","DOI":"10.1002\/jmor.70036","type":"journal-article","created":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T05:10:21Z","timestamp":1740201021000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["On the Fila Olfactoria and the Cribriform Region of the Crocodylia"],"prefix":"10.1002","volume":"286","author":[{"given":"Matthew","family":"Dille","sequence":"first","affiliation":[{"name":"Department of Anatomy, Kirksville College of Osteopathic Medicine AT Still University Kirksville Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Cramberg","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Kirksville College of Osteopathic Medicine AT Still University Kirksville Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadyn","family":"DeLeeuw","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Kirksville College of Osteopathic Medicine AT Still University Kirksville Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Pick","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Kirksville College of Osteopathic Medicine AT Still University Kirksville Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Kirksville College of Osteopathic Medicine AT Still University Kirksville Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0988-7731","authenticated-orcid":false,"given":"Bruce A.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Kirksville College of Osteopathic Medicine AT Still University Kirksville Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470715369.ch10"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(86)90172-3"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12378"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/188547a0"},{"key":"e_1_2_8_6_1","first-page":"213","volume-title":"Paleoneurology of Amniotes: New Directions in the Study of Fossil Endocasts","author":"Barrios F.","year":"2022"},{"key":"e_1_2_8_7_1","first-page":"295","article-title":"Archosaur Phylogeny and the Relationships of the Crocodylia","volume":"1","author":"Benton M. 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