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We investigated one such foramen within the posterior wall of the sella turcica that has been variably described in humans and other primates. We scored foramen presence in humans (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u2009114) and 30 genera of non\u2010human primates (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u20091468), tested its phylogenetic signal, conducted human and macaque dissections, and tracked its developmental onset with newborn and infant baboons. The foramen was present in 12% of humans and 33% of non\u2010human primates, occurring most frequently among hylobatids (77%) and non\u2010human great apes (59%) and least among strepsirrhines (4%), revealing a significant phylogenetic signal (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Phylogenetic generalized least squares showed a strong signal with presence regressed on cranial base angle (CBA), a measure of cranial flexion. Genera with lower presence were more likely to have larger CBAs (Pagel's\n                    <jats:italic>\u03bb<\/jats:italic>\n                    \u2009=\u20090.891), though this signal was strongly driven by\n                    <jats:italic>Homo<\/jats:italic>\n                    . Neither dissections nor developmental histology revealed foramen neurovasculature. However, one fetal and one infant baboon showed spatial constraints by the neurohypophysis, which may compress the sella and delay or prevent local endochondral ossification. We propose formalizing the\n                    <jats:italic>foramen dorsum sellae<\/jats:italic>\n                    and suggest its formation relates to developmental variation in dorsum sellae ossification and remodeling.\n                  <\/jats:p>","DOI":"10.1002\/jmor.70164","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:16:37Z","timestamp":1787746597000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evolutionary Signal and Development of the Foramen Dorsum Sellae (Nov.) Across Primates"],"prefix":"10.1002","volume":"287","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1551-746X","authenticated-orcid":false,"given":"Stephanie L.","family":"Canington","sequence":"first","affiliation":[{"name":"Department of Basic &amp; Translational Sciences University of Pennsylvania School of Dental Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9642-1832","authenticated-orcid":false,"given":"Zana R.","family":"Sims","sequence":"additional","affiliation":[{"name":"Department of Ecology, Evolution, &amp; Behavior University of Minnesota Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6797-9219","authenticated-orcid":false,"given":"Alexandria L.","family":"Sambrano","sequence":"additional","affiliation":[{"name":"Department of Evolutionary Anthropology Duke University Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian A.","family":"Mastroianni","sequence":"additional","affiliation":[{"name":"DMD Program University of Pennsylvania School of Dental Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3912-8821","authenticated-orcid":false,"given":"Michael L.","family":"Platt","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA"},{"name":"Department of Psychology, School of Arts and Sciences University of Pennsylvania Philadelphia Pennsylvania USA"},{"name":"Marketing Department, Wharton School of Business University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6883-8964","authenticated-orcid":false,"given":"Timothy D.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Health and Rehabilitation Sciences, Program of Physical Therapy Slippery Rock University Slippery Rock Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5004-5977","authenticated-orcid":false,"given":"Valerie B.","family":"DeLeon","sequence":"additional","affiliation":[{"name":"Department of Anthropology University of Florida Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8636-0407","authenticated-orcid":false,"given":"Myra F.","family":"Laird","sequence":"additional","affiliation":[{"name":"Department of Basic &amp; Translational Sciences University of Pennsylvania School of Dental Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"issue":"4","key":"e_1_2_10_2_1","first-page":"291","article-title":"The Accessory Foramen Ovale of the Skull: An Osteological Study","volume":"160","author":"Abd Latiff A.","year":"2009","journal-title":"Clinica Terapeutica"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3745"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12304"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-024-04261-5"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/evan.20251"},{"issue":"3","key":"e_1_2_10_7_1","first-page":"239","article-title":"Accessory Osseous Passages in the Vicinity of Foramen Rotundum in a Dry Adult Human Skull: Morphological Evaluation, Embryological Correlation and Clinical Reappraisal","volume":"162","author":"Arora J.","year":"2011","journal-title":"Clinica Terapeutica"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2006.00644.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2010.03.001"},{"issue":"3","key":"e_1_2_10_10_1","first-page":"489","article-title":"Patterns of Cephalofacial Growth and Development. 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