{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T10:39:45Z","timestamp":1769596785010,"version":"3.49.0"},"reference-count":52,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000724","name":"Health Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000724","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Molecular Recognition"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this study, magnetic molecularly imprinted polymers (MMIPs) were prepared and used as sorbents for extraction of S\u2010phenylmercapturic acid (S\u2010PMA) from urine samples, followed by high\u2010performance liquid chromatography ultraviolet\u2010visible (HPLC\u2010UV\/Vis) analysis. The MMIPs were synthesized by the copolymerization reaction of (phenylthio) acetic acid (template molecule), methacrylic acid (functional monomers) and ethylene glycol dimethacrylate (cross\u2010linkers). The morphology, structure property and surface groups of the prepared MMIPs were characterized by scan electron microscopy, transmission electron microscopy, infrared spectroscopy, X\u2010ray diffraction pattern, thermogravimetric analyses, Brunauer\u2010Emmett\u2010Teller and vibrating sample magnetometer. The selectivity of the MMIPs was investigated in the presence of interferents. Various parameters affecting the S\u2010PMA extraction efficiency were investigated, including MMIPs amount, pH, sample volume, desorption solvent, as well as extraction and desorption time. The obtained optimal parameters were as follows: MMIPs amount (20\u2009mg), pH (3.0), sample volume (5\u00a0mL), desorption solvent (methanol\/acetic acid [9\/1, v\/v]), extraction time (30\u2009minutes) and desorption time (2\u00a0minutes). The method was validated according to the Food and Drug Administration Guidance for Industry on Bioanalytical Method Validation. The calibration curve for the analyte was linear in the concentration range of 0.030\u20101.0\u00a0mg\/L (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.9995). The LOD and LOQ of the method were 0.0080 and 0.0267\u2009mg\/L, respectively. The enrichment factor of the MMIPs was 5. The relative standard deviations of intra\u2010 and inter\u2010day tests were in the range of 3.8\u20105.1% and 3.9\u20106.3%, respectively. The recoveries at three different concentrations of 0.10, 0.50 and 0.80\u2009mg\/L ranged between 95.2% and 98.6%. In addition, the MMIPs could be reused for at least eight times. The proposed method was successfully applied to the determination of S\u2010PMA in urine samples. In addition, this developed method could be used as a tool in the early screening and clinical diagnosis of benzene intoxication.<\/jats:p>","DOI":"10.1002\/jmr.2930","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T13:44:43Z","timestamp":1629899083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Magnetic molecularly imprinted polymers for extraction of S\u2010phenylmercapturic acid from urine samples followed by high\u2010performance liquid chromatography"],"prefix":"10.1002","volume":"34","author":[{"given":"Haipeng","family":"Ye","sequence":"first","affiliation":[{"name":"Laboratory of Health testing Hangzhou Occupational Disease Prevention and Control Hospital  Wenhui Street Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji","family":"Shao","sequence":"additional","affiliation":[{"name":"Laboratory of Health testing Hangzhou Occupational 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