{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T02:31:37Z","timestamp":1777343497116,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,7,21]],"date-time":"2003-07-21T00:00:00Z","timestamp":1058745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2003,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To determine the MR imaging findings of autosomal dominant polycystic kidney disease using current imaging techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>We reviewed our five\u2010year experience with MR imaging of autosomal dominant polycystic kidney disease (ADPKD) to determine the spectrum of appearance of kidney disease, the occurrence of cysts in other abdominal organs, the size and number of cysts in the kidneys and other organs, and the association with other benign or malignant disease. Thirty patients (17 men and 13 women, age range 30 to 88 years old) with ADPKD were included in this study. All patients were examined by MR imaging including T2\u2010weighted single\u2010shot echo\u2010train spin\u2010echo and pre\u2010 and post\u2010gadolinium chelate spoiled gradient\u2010echo imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>All kidneys were involved with multiple, varying sized cysts scattered throughout the parenchyma. Giant renal cysts (&gt;8 cm) were associated with pain in the only two patients who possessed them. Hemorrhage in renal cysts was observed in all kidneys with a heterogeneous pattern of involvement on non\u2010contrast T1\u2010 and T2\u2010weighted images, reflecting hemorrhage of varying age. The mean kidney size for the right kidney was 17.4 cm in length, 10.3 cm in transverse, and 9.4 cm in antero\u2010posterior diameter (AP); and for the left kidney, 15.9 cm in the length, 9.3 cm in the transverse, and 9.3 cm in AP diameter. Other organs involved included the liver (22 patients), the pancreas (three patients), with two of the above\u2010mentioned patients having both liver and pancreas cysts, and the spleen (one patient) who had both liver and splenic cysts. Massive liver involvement with large cysts was associated with abdominal pain. Malignant disease was present in five patients, including two patients with renal cell carcinoma, one with bladder cancer, one with lung cancer, and one patient with anal adenocarcinoma. Comparison of pre\u2010 and post\u2010contrast T1\u2010weighted images was essential to detect renal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>All kidneys in patients with ADPKD had extensive, varying\u2010sized cysts and in all cases some cysts showed evidence of hemorrhage. The liver was the second most common organ to be involved with cystic disease, in 73% of patients. Large cysts in the kidneys and liver were associated with abdominal pain. J. Magn. Reson. Imaging 2003;18:210\u2013215. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.10347","type":"journal-article","created":{"date-parts":[[2003,7,22]],"date-time":"2003-07-22T10:12:05Z","timestamp":1058868725000},"page":"210-215","source":"Crossref","is-referenced-by-count":36,"title":["Autosomal dominant polycystic kidney disease: MR imaging evaluation using current techniques"],"prefix":"10.1002","volume":"18","author":[{"given":"Maria 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