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The authors studied the movement of water molecules in each type of white matter edema in a rat model by using diffusion\u2010weighted magnetic resonance imaging. Conventional T2\u2010weighted imaging did not allow distinction between the three types of white matter edema; the three types of edema were, however, distinguished by using diffusion\u2010weighted imaging. The apparent diffusion coefficient (ADC) of water was different in each type of edema. Water molecules in cytotoxic edema induced by triethyl\u2010tin intoxication showed a smaller and less anisotropic ADC than in normal white matter. In contrast, water in vasogenic edema induced by cold injury had a larger and more anisotropic ADC than in normal white matter. Water in interstitial edema due to kaolin\u2010induced hydrocephalus had an anisotropic and very large ADC.<\/jats:p>","DOI":"10.1002\/jmri.1880030612","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T03:05:51Z","timestamp":1173150351000},"page":"863-868","source":"Crossref","is-referenced-by-count":122,"title":["Discrimination between different types of white matter edema with diffusion\u2010weighted MR 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