{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T07:34:33Z","timestamp":1791012873554,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T00:00:00Z","timestamp":1133827200000},"content-version":"vor","delay-in-days":3688,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[1995,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The signal loss that occurs in regions of disturbed flow significantly decreases the clinical usefulness of MR angiography in the imaging of diseased arteries. This signal loss is most often attributed to turbulent flow; but on a typical MR angiogram, the signal is lost in the nonturbulent upstream region of the stenosis as well as in the turbulent downstream region. In the current study we used a flow phantom with a forward\u2010facing step geometry to model the upstream region. The flow upstream of the step was convergent, which created high levels of convective acceleration. This region of the flow field contributes to signal loss at the constriction, leading to overestimation of the area of stenosis reduction. A computer program was designed to simulate the image artifacts that would be caused by this geometry in two\u2010dimensional time\u2010of\u2010flight MR angiography. Simulated images were compared with actual phantom images and the flow artifacts were highly correlated. The computer simulation was then used to test the effects of different orders of motion compensation and of fewer pixels per diameter, as would be present in MR angiograms of small arteries. The results indicated that the computational simulation of flow artifacts upstream of the stenosis provides an important tool in the design of optimal imaging sequences for the reduction of signal loss.<\/jats:p>","DOI":"10.1002\/jmri.1880050610","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T04:40:22Z","timestamp":1173156022000},"page":"677-683","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of phantom and computer\u2010simulated MR images of flow in a convergent geometry: Implications for improved two\u2010dimensional MR angiography"],"prefix":"10.1002","volume":"5","author":[{"suffix":"Jr","given":"John M.","family":"Siegel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John N.","family":"Oshinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roderic I.","family":"Pettigrew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David N.","family":"Ku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.1986.4307763"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910100106"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.175.3.2343137"},{"key":"e_1_2_1_5_2","first-page":"364","volume-title":"Proceedings of the Society of Magnetic Resonance in Medicine 1991","author":"Gatenby JC","year":"1991"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.178.1.1984310"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880010512"},{"key":"e_1_2_1_8_2","first-page":"2814","volume-title":"Proceedings of the Society of Magnetic Resonance in Medicine 1992","author":"Gatenby JC","year":"1992"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880020415"},{"key":"e_1_2_1_10_2","volume-title":"Use of magnetic resonance imaging to evaluate stenotic flows (dissertation)","author":"Oshinski JN","year":"1993"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910330208"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-1752-5"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1067\/mva.1992.39289"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910140215"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/153100359000300106"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-198807000-00006"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880020610"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910220255"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(89)90548-1"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.1880050610","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.1880050610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T22:27:37Z","timestamp":1698272857000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.1880050610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1995,11]]}},"alternative-id":["10.1002\/jmri.1880050610"],"URL":"https:\/\/doi.org\/10.1002\/jmri.1880050610","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,11]]}}}