{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:20:10Z","timestamp":1774354810074,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T00:00:00Z","timestamp":1133827200000},"content-version":"vor","delay-in-days":3688,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[1995,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For patients with persistent or recurrent hyperpara\u2010thyroldism, parathyroid imaging is indicated to confirm the presence of abnormal parathyroid gland(s) and identify their location. These imaging techniques are being modified constantly and newer methods have been developed. Sestamibi scintigraphy, MRI and sonography were compared in 23 patients with persistent or recurrent hyperparathyroidism. Preoperative 99m\u2010Technetium Sestamibi (MIBI), MRI and ultraaono\u2010graphic (US) studies of 23 patients with 25 histopatho\u2010logically confirmed abnormal parathyroid glands were compared, using independent prospective interpretations. All patients had been operated upon previously for hyperparthytroidism. Accuracy of various combinations of MRI. MIBI, and US also were calculated. The results are shown for all abnormal glands (<jats:italic>n<\/jats:italic> = 25): sensitivities and accuracies were 88 and 84% for MRI. 80 and 80% for MIBI. and 58 and 44% for U<jats:italic>S<\/jats:italic>. For only parathyroid adenomas (<jats:italic>n<\/jats:italic> = 18). sensitivities and accuracies were 89 and 89% for MRI, 94 and 94% for MIBI. and 58 and 39% for U<jats:italic>S.<\/jats:italic> Finally, for parathyroid hyperplasla (<jats:italic>n<\/jats:italic> = 7 glands in five patients), sensitivities and accuracies were 83 and 71% for MRI. 43 and 43% for MIBI, and 57 and 57% for U<jats:italic>S.<\/jats:italic> Either MIBI or MRI results were significantly better for detecting abnormal parathyroid glands than US (<jats:italic>P<\/jats:italic> &lt;0.01), but MRI and MIBI were not statistically different. Combining MRI and MIBI produced a combined accuracy of 92%, whereas combining either of these tests with US did not improve on the accuracy of either test alone. In conclusion, for patients with persistent or recurrent hyperparathyroidism, MRI and MIBI are equally accurate for detecting abnormal parathyroid glands, and the combination of both tests may be more accurate than either test alone.<\/jats:p>","DOI":"10.1002\/jmri.1880050614","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T04:40:22Z","timestamp":1173156022000},"page":"702-708","source":"Crossref","is-referenced-by-count":39,"title":["Hyperparathyroidism: A comparison of sestamibi scintigraphy, mri, and ultrasonography"],"prefix":"10.1002","volume":"5","author":[{"given":"Leonard M.","family":"Numerow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene T.","family":"Morita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orlo H.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles B","family":"Higgins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1975.01360110171028"},{"key":"e_1_2_1_3_2","first-page":"1083","article-title":"Localization studies in patients with persistent or recurrent hyperparathyroidism","volume":"98","author":"Clark OH","year":"1985","journal-title":"Surgery"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198203000-00001"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-2998(78)80013-0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.162.1.3538146"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.162.1.3538145"},{"key":"e_1_2_1_8_2","first-page":"917","article-title":"Localizing studies in patients with persistent or recurrent hyperparathyroidism","volume":"102","author":"Levin KE","year":"1987","journal-title":"Surgery"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.150.5.1027"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.160.3.8430565"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(89)90703-0"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.163.2.3562820"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.189.1.8372183"},{"key":"e_1_2_1_14_2","first-page":"313","article-title":"Parathyroid imaging with technetrium\u201099m\u2010sestamibi: preoperative localization and tissue uptake studies","volume":"33","author":"O'Doherty MJ","year":"1992","journal-title":"J Nucl Med"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00182301"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199310000-00060"},{"key":"e_1_2_1_17_2","first-page":"166P","volume-title":"Proceedings of the 40th Annual Meeting of the Society of Nuclear Medicine: 1993 June 8\u201311","author":"Palestro CJ","year":"1993"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1994.01420320096019"},{"key":"e_1_2_1_19_2","first-page":"1111","article-title":"Prospective evaluation of the efficacy of technetium 99m sestamibi and iodine 123 radionuclide imaging of abnormal parathyroid glands","volume":"112","author":"Wei JP","year":"1992","journal-title":"Surgery"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.78.1.77"},{"key":"e_1_2_1_21_2","first-page":"165P","volume-title":"Proceedings of the 40th Annual Meeting of the Society of Nuclear Medicine; 1993 June 8\u201311","author":"Varma VM","year":"1993"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.1880050614","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.1880050614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T22:27:51Z","timestamp":1698272871000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.1880050614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1995,11]]}},"alternative-id":["10.1002\/jmri.1880050614"],"URL":"https:\/\/doi.org\/10.1002\/jmri.1880050614","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,11]]}}}