{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T22:15:43Z","timestamp":1789596943206,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,11,17]],"date-time":"2005-11-17T00:00:00Z","timestamp":1132185600000},"content-version":"vor","delay-in-days":2938,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[1997,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to determine the potential value of rectally administered Ferumoxsil for pelvic MRI. Twenty patients with suspected rectosigmoid and ovarian tumors were prospectively examined before and after rectal administration of 300 to 600 ml of the superparamagnetic contrast agent Ferumoxsil. Imaging parameters (1.5\u2010T system, phased\u2010array coil, transverse T1\u2010weighted spin echo (SE) and T2\u2010weighted turbo\u2010SE sequences, 6\u2010mm slice thickness, 350\u2010mm field of view [FOV], 512 \u00d7 512 matrix) were kept constant. Images were evaluated for tumor presence, lymphadenopathy, bowel involvement, and peritoneal implants. Precontrast and postcontrast studies were rated for bowel delineation, lesion\/organ\u2010to\u2010bowel differentiation, presence of artifacts, and confidence of diagnosis. Delineation of rectum and sigmoid colon (<jats:italic>P<\/jats:italic> &lt; .001) as well as separation of bowel and vagina, uterus\/adnexa, dome of the urinary bladder, lymph nodes, and vessels improved significantly (<jats:italic>P<\/jats:italic> &lt; .01) on both T1\u2010weighted and T2\u2010weighted postcontrast sequences. The rectal contrast agent did not increase the level of artifacts. Changes in diagnosis in 7 of 20 patients were mainly due to identification of colorectal tumors or bowel involvement on postcontrast images. The readers' diagnostic confidence was significantly higher on contrast\u2010enhanced than on unenhanced studies (93 \u00b1 6.4% vs 68 \u00b1 25.2%). Rectal application of Ferumoxsil improves lesion\/organ\u2010to\u2010bowel delineation and overall diagnostic confidence in pelvic MRI.<\/jats:p>","DOI":"10.1002\/jmri.1880070614","type":"journal-article","created":{"date-parts":[[2007,3,16]],"date-time":"2007-03-16T10:05:55Z","timestamp":1174039555000},"page":"1027-1032","source":"Crossref","is-referenced-by-count":14,"title":["MRI of pelvic masses: Efficacy of the rectal superparamagnetic contrast agent ferumoxsil"],"prefix":"10.1002","volume":"7","author":[{"given":"Juergen","family":"Scheidler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas F.","family":"Heuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Meier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian F.","family":"Reiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,17]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-66-785-420"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880030118"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.175.3.2343116"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880050404"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/02841859109177554"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(05)81159-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-66-785-415"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.178.3.1994417"},{"key":"e_1_2_1_10_2","first-page":"93","article-title":"Safety and efficacy of superparamagnetic iron oxide: summary of multicenter phase II\u2010III clinical trials","volume":"181","author":"Ros PR","year":"1991","journal-title":"Radiology"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880030119"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.11.5.1947314"},{"issue":"1","key":"e_1_2_1_13_2","first-page":"82","article-title":"Oral magnetic particles as a contrast agent for MR imaging of the abdomen. A phase III clinical trial","volume":"41","author":"Vlahos L","year":"1994","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.261.3.420"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880020312"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.161.3.8352116"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(92)90002-H"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.191.3.8184076"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880060309"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.189.2.8210368"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.155.5.2120945"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910300518"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880010515"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.1880070614","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.1880070614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T00:42:38Z","timestamp":1698453758000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.1880070614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,11]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1997,11]]}},"alternative-id":["10.1002\/jmri.1880070614"],"URL":"https:\/\/doi.org\/10.1002\/jmri.1880070614","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,11]]}}}