{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:13:48Z","timestamp":1791245628017,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,7,18]],"date-time":"2005-07-18T00:00:00Z","timestamp":1121644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate the diffusion tensor properties of the human optic nerve in vivo using a non\u2010Carr\u2010Purcell\u2010Meiboom\u2010Gill (CPMG) fast spin echo (FSE) sequence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This non\u2010CPMG FSE sequence, which is based on a quadratic phase modulation of the refocusing pulses, allows diffusion measures to be acquired with full signal and without artifacts from geometric distortions due to magnetic field inhomogeneities, which are among the main problems encountered in the orbital area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Good\u2010quality images were obtained at a resolution of 0.94 \u00d7 0.94 \u00d7 3 mm. The mean diffusivity (MD) and fractional anisotropy (FA) were respectively 1.1 \u00b1 0.2 \u00d7 10<jats:sup>\u20133<\/jats:sup> mm<jats:sup>2<\/jats:sup>\/second and 0.49 \u00b1 0.06, reflecting the optic nerve anisotropy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This non\u2010CPMG\u2010FSE sequence provides reliable diffusion\u2010weighted images of the human optic nerve. This approach could potentially improve the diagnosis and management of optic nerve diseases or compression, such as optic neuritis, orbit tumors, and muscle hypertrophy. J. Magn. Reson. Imaging 2005;22:307\u2013310. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.20383","type":"journal-article","created":{"date-parts":[[2005,7,18]],"date-time":"2005-07-18T19:47:50Z","timestamp":1121716070000},"page":"307-310","source":"Crossref","is-referenced-by-count":41,"title":["Diffusion tensor imaging of the human optic nerve using a non\u2010CPMG fast spin echo sequence"],"prefix":"10.1002","volume":"22","author":[{"given":"Steren","family":"Chabert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Molko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Cointepas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Le Roux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Le Bihan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,7,18]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01148-X"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1119"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.787"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910380317"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910310408"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(01)00490-7"},{"key":"e_1_2_5_8_2","volume-title":"Walsh and Hoyt's clinical neuro\u2010ophthalmology","author":"Miller NR","year":"1982"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1088\/0022-3719\/10\/3\/004"},{"key":"e_1_2_5_10_2","unstructured":"FreemanAJ BallingerR WernerM. et al.Diffusion weighted EPI of the human optic nerve at 3 T. 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