{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:44:03Z","timestamp":1792604643545,"version":"4.5.0"},"reference-count":48,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,9,6]],"date-time":"2006-09-06T00:00:00Z","timestamp":1157500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate the contribution of perfusion\u2010weighted MR imaging (PWI) by using the relative cerebral blood volume (rCBV) ratio in the differential diagnosis of various intracranial space\u2010occupying lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This study involved 105 patients with lesions (high\u2010grade glioma (<jats:italic>N<\/jats:italic> = 26), low\u2010grade glioma (<jats:italic>N<\/jats:italic>= 11), meningioma (<jats:italic>N<\/jats:italic> = 23), metastasis (<jats:italic>N<\/jats:italic> = 25), hemangioblastoma (<jats:italic>N<\/jats:italic> = 6), pyogenic abscess (<jats:italic>N<\/jats:italic> = 4), schwannoma (<jats:italic>N<\/jats:italic> = 5), and lymphoma (<jats:italic>N<\/jats:italic> = 5)). The patients were examined with a T2*\u2010weighted (T2*W) gradient\u2010echo single\u2010shot EPI sequence. The rCBV ratios of the lesions were obtained by dividing the values obtained from the normal white matter. Statistical analysis was performed with the Mann\u2010Whitney U\u2010test. A <jats:italic>P<\/jats:italic>\u2010value less than 0.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The rCBV ratio was 5.76 \u00b1 3.35 in high\u2010grade gliomas, 1.69 \u00b1 0.51 in low\u2010grade gliomas, 8.02 \u00b1 3.89 in meningiomas, 5.27 \u00b1 3.22 in metastases, 11.36 \u00b1 4.41 in hemangioblastomas, 0.76 \u00b1 0.12 in abscesses, 1.10 \u00b1 0.32 in lymphomas, and 3.23 \u00b1 0.81 in schwannomas. The rCBV ratios were used to discriminate between 1) high\u2010 and low\u2010grade gliomas (<jats:italic>P<\/jats:italic> &lt; 0.001), 2) hemangioblastomas and metastases (<jats:italic>P<\/jats:italic>&lt; 0.05), 3) abscesses from high\u2010grade gliomas and metastases (<jats:italic>P<\/jats:italic> &lt; 0.001), 4) schwannomas and meningiomas (<jats:italic>P<\/jats:italic> &lt; 0.001), 5) lymphomas from high\u2010grade gliomas and metastases (<jats:italic>P<\/jats:italic> &lt; 0.001), and 6) typical meningiomas and atypical meningiomas (<jats:italic>P<\/jats:italic> &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>rCBV ratios can help discriminate intracranial space\u2010occupying lesions by demonstrating lesion vascularity. It is possible to discriminate between 1) high\u2010 and low\u2010grade gliomas, 2) hemangioblastomas and other intracranial posterior fossa masses, 3) abscesses from high\u2010grade gliomas and metastases, 4) schwannomas and meningiomas, 5) lymphomas and high\u2010grade gliomas and metastases, and 6) typical and atypical meningiomas. J. Magn. Reson. Imaging 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.20707","type":"journal-article","created":{"date-parts":[[2006,9,6]],"date-time":"2006-09-06T17:21:43Z","timestamp":1157563303000},"page":"817-824","source":"Crossref","is-referenced-by-count":190,"title":["Evaluation of different cerebral mass lesions by perfusion\u2010weighted MR 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