{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:57:10Z","timestamp":1761058630144},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,2,26]],"date-time":"2007-02-26T00:00:00Z","timestamp":1172448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess whether the use of postcontrast fluid\u2010attenuated inversion recovery (FLAIR) imaging in combination with pre\u2010 and postcontrast magnetization transfer (MT) T1\u2010weighted imaging (T1WI) can increase diagnostic confidence in the evaluation of brain metastases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Brain MR images from 41 patients with suspected brain metastases were reviewed. Two radiologists viewed pre\u2010 and postcontrast MT\u2010T1W images for the presence of metastatic tumors and rated the possible enhanced lesions using a five\u2010point confidence scale (session 1). The postcontrast FLAIR images were then viewed together with pre\u2010 and postcontrast MT\u2010T1W images, and the presence of metastasis was rated again (session 2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 240 possible enhanced lesions were detected in session 1. Judging by follow\u2010up MR examinations, 196 were considered to be nonmetastatic findings and 44 were determined to be metastasis. In session 2 the confidence rating for nonmetastasis increased significantly in the subset of nonmetastatic findings (<jats:italic>P<\/jats:italic> &lt; 0.001), and the confidence rating for metastasis increased significantly in the subset of metastases (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The addition of postcontrast FLAIR imaging to pre\u2010 and postcontrast MT\u2010T1WI improves diagnostic confidence in evaluation of brain metastases. J. Magn. Reson. Imaging 2007;25:479\u2013487. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.20847","type":"journal-article","created":{"date-parts":[[2007,2,26]],"date-time":"2007-02-26T17:39:47Z","timestamp":1172511587000},"page":"479-487","source":"Crossref","is-referenced-by-count":25,"title":["Contrast\u2010enhanced FLAIR imaging in combination with pre\u2010 and postcontrast magnetization transfer T1\u2010weighted imaging: Usefulness in the evaluation of brain metastases"],"prefix":"10.1002","volume":"25","author":[{"given":"Satoshi","family":"Terae","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohsuke","family":"Kudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khin 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