{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:05:59Z","timestamp":1790845559535,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T00:00:00Z","timestamp":1172793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess the effect of diuretic administration on the image quality of excretory magnetic resonance urography (MRU) obtained following intravenous hydration, and to determine whether intravenous hydration alone is sufficient to produce diagnostic quality studies of nondilated upper tracts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 22 patients with nondilated upper tracts were evaluated with contrast\u2010enhanced MRU. All patients received 250 mL of saline intravenously immediately prior to the examination. A total of 11 patients received 10\u201320 mg furosemide in addition to saline. Imaging was performed with a three\u2010dimensional (3D) and two\u2010dimensional (2D) breathhold spoiled gradient\u2010echo sequences. Excretory MRU images were acquired five minutes after the administration of 0.1 mmol\/kg gadolinium and were independently reviewed by two radiologists, who were blinded to the MRU technique. Readers evaluated the calyces, renal pelvis, and ureters qualitatively for degree of opacification, distention, and artifacts on a four\u2010point scale. Statistical analysis was performed using a permutation test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant disagreement between the two readers (<jats:italic>P<\/jats:italic> = 0.14). Furosemide resulted in significant improvement in calyceal and renal pelvis distention (<jats:italic>P<\/jats:italic> &lt; 0.005), and significant artifact reduction in all upper tract segments (<jats:italic>P<\/jats:italic> &lt; 0.001) compared to the effect of saline alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intravenous furosemide significantly improves the image quality of excretory MRU studies obtained following intravenous hydration. Intravenous saline alone is insufficient to produce diagnostic quality studies of the non\u2010dilated upper tracts. J. Magn. Reson. Imaging 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.20875","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:40:24Z","timestamp":1172882424000},"page":"783-789","source":"Crossref","is-referenced-by-count":42,"title":["3D excretory MR urography: Improved image quality with intravenous saline and diuretic administration"],"prefix":"10.1002","volume":"25","author":[{"given":"F. 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