{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:42:29Z","timestamp":1791520949934,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,8,29]],"date-time":"2007-08-29T00:00:00Z","timestamp":1188345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To measure <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> and <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> of the fine structures of the in vivo eye.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Involuntary saccades make it difficult to obtain artifact\u2010free images. Using a method recently reported (Bert et al, <jats:italic>Acad Radiol<\/jats:italic> 2006;12:368\u2013378), near artifact\u2010free spin\u2010echo images were obtained. Both an isolated enucleated eye and eight human subjects were studied at 1.5T. Spin\u2010echo variable <jats:italic>TR<\/jats:italic>\/<jats:italic>TE<\/jats:italic> data was acquired for <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub>\/<jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> determination. Average relaxation times were calculated two ways. First, an arithmetic average over different subjects was computed. Second, all data was normalized using the fitted amplitudes of each data set and pooled to obtain a single least squares fit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In vivo <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub>\/<jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> (msec) are: arithmetic average <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub>, <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>, normalized data <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub>, <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>. Anterior chamber: 6233 \u00b1 979, 468 \u00b1 149, 5053 \u00b1 1052, 450 \u00b1 49. Ciliary body: 1916 \u00b1 184, 80 \u00b1 7, 2038 \u00b1 114, 76 \u00b1 3. Chorioretina: 1717 \u00b1 500, 72 \u00b1 25, 1511 \u00b1 230, 78 \u00b1 3. Extraocular muscle: 1581 \u00b1 646, 41 \u00b1 7, 1470 \u00b1 231, 41 \u00b1 1. Iris: 3334 \u00b1 989, 163 \u00b1 63, 3376 \u00b1 338, 153 \u00b1 10. Lens cortex: 1712 \u00b1 466, 93 \u00b1 36, 1413 \u00b1 177, 100 \u00b1 5. Lens nucleus: 1133 \u00b1 40, 26 \u00b1 3, 1138 \u00b1 47, 25 \u00b1 0.4. Optic nerve: 1906 \u00b1 301, 68 \u00b1 16, 1805 \u00b1 244, 71 \u00b1 2. Posterior chamber: 7915 \u00b1 4897, 241 \u00b1 14, 3323 \u00b1 2154, 251 \u00b1 38. Vitreous humor: 5768 \u00b1 1190, 756 \u00b1 804, 4855 \u00b1 1846, 390 \u00b1 8.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In vivo <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> and <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> for many of the fine structures of the human eye have been measured. J. Magn. Reson. Imaging 2007;26:510\u2013518. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.21017","type":"journal-article","created":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T03:47:24Z","timestamp":1188445644000},"page":"510-518","source":"Crossref","is-referenced-by-count":28,"title":["<i>T<\/i><sub>1<\/sub> and <i>T<\/i><sub>2<\/sub> measurements of the fine structures of the in vivo and enucleated human eye"],"prefix":"10.1002","volume":"26","author":[{"given":"Samuel","family":"Patz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Bert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Frederick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F.","family":"Freddo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,8,29]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"141","article-title":"Surface coil MR of orbital pseudotumor","volume":"8","author":"Atlas SW","year":"1987","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.156.3.4023227"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.152.1.6729139"},{"key":"e_1_2_6_5_2","first-page":"253","article-title":"0.6T magnetic resonance imaging of the orbit","volume":"6","author":"Edwards JF","year":"1983","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.158.2.3941871"},{"key":"e_1_2_6_7_2","first-page":"254","article-title":"NMR imaging in the evaluation of orbital tumors","volume":"4","author":"Hawkes RC","year":"1983","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.150.3.6695076"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.160.3.3737917"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.67.6.333"},{"key":"e_1_2_6_11_2","first-page":"345","article-title":"NMR of the normal and pathologic eye and orbit","volume":"5","author":"Sobel DF","year":"1984","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_12_2","first-page":"259","article-title":"MR imaging of orbital and ocular disease","volume":"6","author":"Sobel DF","year":"1985","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_13_2","first-page":"29","article-title":"Surface\u2010coil MR imaging of orbital neoplasms","volume":"7","author":"Sullivan JA","year":"1986","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.164.2.3602393"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00587815"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00240700"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-003-0954-8"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.6.747"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.160.1.3715033"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2001.01220.x"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2005.10.023"},{"key":"e_1_2_6_22_2","series-title":"Encylopedia of environmetrics","first-page":"1405","author":"Smyth GK","year":"2002"},{"key":"e_1_2_6_23_2","first-page":"111","volume-title":"Magnetic resonance imaging: physical principles and sequence design","author":"Haacke ME","year":"1999"},{"key":"e_1_2_6_24_2","first-page":"182","volume-title":"Introduction to electromagnetic fields and waves","author":"Corson D","year":"1962"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1006\/exer.1999.0812"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0730-725X(02)00481-2"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1080\/00268978900101531"},{"key":"e_1_2_6_28_2","first-page":"320","volume-title":"Nuclear magnetic resonance imaging in medicine and biology","author":"Morris PG","year":"1986"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2005.07.019"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.21017","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.21017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T05:17:47Z","timestamp":1697087867000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.21017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,29]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1002\/jmri.21017"],"URL":"https:\/\/doi.org\/10.1002\/jmri.21017","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,29]]}}}