{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:56:40Z","timestamp":1761541000204},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,2,25]],"date-time":"2009-02-25T00:00:00Z","timestamp":1235520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare 3.0T and 1.5T MR systems in terms of the effect of superparamagnetic iron oxide (SPIO) on tumor\u2010to\u2010liver contrast in T2*\u2010weighted gradient\u2010echo MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>SPIO\u2010enhanced gradient\u2010echo MR images of the liver with four different TEs (3, 5.3, 6.5, and 8.5 msec) were obtained by means of 1.5T and 3.0T systems. Quantitative analyses of relative signal intensities (SIs) and relative tumor contrast and qualitative analyses of image quality and lesion conspicuity of the liver were performed in 22 patients, 16 of whom had malignant liver tumors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>With both 1.5T and 3.0T, at TE = 8.4 msec, the relative SI of liver and relative tumor contrast were significantly (<jats:italic>P<\/jats:italic> &lt; 0.01) lower and higher, respectively, than that for any of the other TEs. There were no significant differences in the relative SI of the liver, relative tumor contrast, image quality, and tumor conspicuity for the same TE between the 1.5T and 3.0T systems.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results showed that the effect of SPIO on tumor\u2010to\u2010liver contrast at T2*\u2010weighted gradient\u2010echo imaging was similar for the 1.5T and 3.0T systems, and that the 8.4\u2010msec TE was optimal of the four TEs used in this study at 3.0T. J. Magn. Reson. Imaging 2009;29:595\u2013600. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.21384","type":"journal-article","created":{"date-parts":[[2010,7,9]],"date-time":"2010-07-09T15:48:05Z","timestamp":1278690485000},"page":"595-600","source":"Crossref","is-referenced-by-count":17,"title":["Effect of superparamagnetic iron oxide on tumor\u2010to\u2010liver contrast at T2*\u2010weighted gradient\u2010echo MRI: Comparison between 3.0T and 1.5T MR 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