{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T09:12:16Z","timestamp":1775812336090,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,9,28]],"date-time":"2009-09-28T00:00:00Z","timestamp":1254096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the feasibility of a multi\u2010station three dimensional (3D) T1\u2010weighted turbo spin echo (TSE) dark\u2010blood Sampling Perfection with Application optimized Contrasts using different flip angle Evolution sequence (T1w\u2010SPACE), to assess aorta, iliac, and superficial femoral (SFA) arteries (inflow vessels) by comparing it with a multi\u2010station contrast enhanced MR angiography (CE\u2010MRA) with identical resolution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 6 volunteers and 14 peripheral arterial disease (PAD) patients were included in the study. Abdominal and thigh T1w\u2010SPACE and lower leg time\u2010resolved MRA (TR\u2010MRA) with low dose contrast were followed by 3\u2010station CE\u2010MRA. Quantitative measurements of lumen area at 17 locations from T1w\u2010SPACE and CE\u2010MRA were obtained. Additionally, vessel wall areas at the same locations were obtained from the T1w\u2010SPACE images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Quantitative comparison of lumen areas with T1w\u2010SPACE and CE\u2010MRA revealed strong correlation between the two techniques and strong inter\u2010observer agreement for each of the two imaging methods (r &gt; 0.9; <jats:italic>P<\/jats:italic> &lt; 0.001). Localized vessel wall area measurements obtained in PAD patients were significantly greater compared with those obtained in normal volunteers (mean difference 43.75 \u00b1 12.46 mm<jats:sup>2<\/jats:sup>; <jats:italic>P<\/jats:italic> &lt; 0.001). Stenosis severity obtained from T1w\u2010SPACE localized measurements showed significant arterial area stenosis in PAD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>T1w\u2010SPACE imaging of inflow vessels is feasible, and in addition to CE\u2010MRA has the ability to assess atherosclerotic plaque and vascular remodeling. J. Magn. Reson. Imaging 2009;30:785\u2013793. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.21923","type":"journal-article","created":{"date-parts":[[2009,9,28]],"date-time":"2009-09-28T16:05:57Z","timestamp":1254153957000},"page":"785-793","source":"Crossref","is-referenced-by-count":31,"title":["Initial feasibility of a multi\u2010station high resolution three\u2010dimensional dark blood angiography protocol for the assessment of peripheral arterial disease"],"prefix":"10.1002","volume":"30","author":[{"given":"Georgeta","family":"Mihai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiu\u2010Cho","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mbabazi","family":"Kariisa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subha 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