{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:44:57Z","timestamp":1789991097233,"version":"4.0.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2009,12,20]],"date-time":"2009-12-20T00:00:00Z","timestamp":1261267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To enable volume visualization of endolymphatic hydrops of M\u00e9ni\u00e8re's disease via a volume rendering (VR) technique, a three\u2010dimensional (3D) inversion\u2010recovery (IR) sequence with real reconstruction (3D\u2010real IR) sequence after intratympanic injection of Gd\u2010DTPA was optimized for higher spatial resolution using a 32\u2010channel head coil at 3T.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods:<\/jats:title><jats:p>Pulse sequence parameters were optimized using a diluted Gd\u2010DTPA phantom. Then, 11 patients who had been clinically diagnosed with M\u00e9ni\u00e8re's disease and a patient with sudden hearing loss were scanned. Images were processed using commercially available 3D\u2010VR software. 3D\u2010real IR data was processed to produce endolymph and perilymph fluid volume images in different colors. 3D\u2010CISS data was processed to generate total fluid volume images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>While maintaining a comparable signal\u2010to\u2010noise ratio (SNR) and scan time, the voxel volume could be reduced from 0.4 \u00d7 0.4 \u00d7 2 mm<jats:sup>3<\/jats:sup> with a 12\u2010channel coil to 0.4 \u00d7 0.4 \u00d7 0.8 mm<jats:sup>3<\/jats:sup> with a 32\u2010channel coil. A newly\u2010optimized protocol allowed the smooth, three\u2010dimensional visualization of endolymphatic hydrops in all patients with M\u00e9ni\u00e8re's disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Volumetrically separate visualization of endo\u2010\/perilymphatic space is now feasible in patients with M\u00e9ni\u00e8re's disease using an optimized 3D\u2010real IR sequence, a 32\u2010channel head coil, at 3T, after intratympanic administration of Gd\u2010DTPA. This will aid the understanding of the pathophysiology of M\u00e9ni\u00e8re's disease. J. Magn. Reson. Imaging 2010;31:210\u2013214. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmri.22012","type":"journal-article","created":{"date-parts":[[2009,12,21]],"date-time":"2009-12-21T05:04:18Z","timestamp":1261371858000},"page":"210-214","source":"Crossref","is-referenced-by-count":35,"title":["Three\u2010dimensional (3D) visualization of endolymphatic hydrops after intratympanic injection of Gd\u2010DTPA: Optimization of a 3D\u2010real inversion\u2010recovery turbo spin\u2010echo (TSE) sequence and application of a 32\u2010channel head coil at 3T"],"prefix":"10.1002","volume":"31","author":[{"given":"Shinji","family":"Naganawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunichi","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Iwano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michihiko","family":"Sone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Nakashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,12,20]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199905000-00013"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31802c300c"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0894"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-0854-8"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480902729868"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.7.85"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20925"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480902729827"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050015"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2004.01.021"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1110"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480902729868"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.8.43"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480600621722"}],"container-title":["Journal of Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmri.22012","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmri.22012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T05:02:58Z","timestamp":1697518978000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmri.22012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12,20]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1002\/jmri.22012"],"URL":"https:\/\/doi.org\/10.1002\/jmri.22012","archive":["Portico"],"relation":{},"ISSN":["1053-1807","1522-2586"],"issn-type":[{"value":"1053-1807","type":"print"},{"value":"1522-2586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12,20]]}}}